Acquisition of a High Field Solid State NMR Spectrometer

购置高场固态核磁共振波谱仪

• 批准号: 0216201
• 负责人: Gina Hoatson
• 金额: $ 77万
• 依托单位: College of William and Mary
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-15 至 2005-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0216201&HistoricalAwards=false
• 关键词: Acquisition; Field; Solid; State; NMR

With support from the Major Research Instrumentation (MRI) Program at NSF, and the Department of Defense, Profs. Gina Hoatson and Robert Vold at the College of William and Mary will acquire a high field (18 tesla), multinuclear solid state nuclear magnetic resonance (NMR) Spectrometer. This equipment will enable researchers to carry out studies on a) ferroelectric and piezoelectric materials; b) high performance carbon nitride films; c) technologically important conducting polymers; and d) biologically important amino acids and cyclic dipeptides. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential for carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including development of wear-related coatings, ultrasonic transducers and electronic actuators, and electrochromic devices. In addition, amino acids and cyclic dipeptides are important to study because these model systems yield insight into problems of protein folding, molecular recognition and enzyme activity.

在NSF的主要研究仪器（MRI）计划和国防部的支持下，威廉和玛丽学院的吉娜·霍特森和罗伯特·沃尔德将获得一台高场（18特斯拉）多核固态核磁共振（NMR）光谱仪。该设备将使研究人员能够进行以下研究：a）铁电和压电材料; B）高性能氮化碳薄膜; c）技术上重要的导电聚合物; d）生物上重要的氨基酸和环二肽。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 获得最先进的核磁共振光谱仪对于开展前沿研究至关重要。这些NMR研究的结果将对许多领域产生影响，包括与磨损相关的涂层，超声波换能器和电子致动器以及电致变色设备的开发。 此外，氨基酸和环二肽是重要的研究，因为这些模型系统产生洞察蛋白质折叠，分子识别和酶活性的问题。