Conference: Sixth International Symposium On Cytochome P450 Biodiversity, to be held in Los Angeles, California, August 20-25, 2002

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The cytochrome P450 monooxygenase superfamily of heme-containing enzymes contains a widerange of monooxygenase activities that make them critically important to virtually alllife forms. In recent years, they have been shown to be important in human growth anddevelopment because they are involved in steroid biosynthesis and also in manypharmacological areas because they are critical for the activation and/or detoxificationof drugs in human and vertebrate models. In a rapidly and ever-expanding area, they havebeen shown to be important in insect and plant growth and development because of theirinvolvement in biosynthetic pathways for insect and plant hormones and in agriculturalareas because they mediate the metabolism of herbicides, insecticides, fungicides andenvironmental pollutants.Realizing the growing importance of this area of plant and insect P450 research, theorganizing committee for the International Symposium Series on P450 Biodiversity branchedfrom the more classical area of vertebrate P450 research represented in the SymposiumSeries on Microsomes and Drug Oxidations to create an independent and focused seriesdevoted to microorganisms, plants and insects. For the Sixth International Symposium onP450 Biodiversity: Functional Biochemistry & Molecular Biology of P450 Cytochromes inMicroorganisms, Plants and Insects, the organizers have endeavored to continue theexamples set in the five previous meetings in this series by providing platforms for thepresentation of approaches for expression analysis of model P450s as well as functionalanalysis of the numerous P450s existing in these non-vertebrate systems. The goal is toprovide a forum for discussing leading research in the field through a single lectureseries of 48 presentations interspersed with scheduled poster presentations and ample timefor informal discussions. With this goal in mind, funds are requested to help supporttravel expenses for competitively identified advanced predoctoral and postdoctoralstudents.The International Advisory Board and Scientific Organizing Committee for this Seriescontains representatives from seven different countries including eleven from the UnitedStates. The meeting will be held August 20-25, 2002 at the Conference Center on the UCLAcampus and hosted by Armand J. Fulco, Professor of Biochemistry at the University ofCalifornia, Los Angeles (UCLA). Dr. Fulco's research has focused on characterization ofbacterial cytochrome P450s through a variety of world-wide collaborations. It is expectedthat attendance at this meeting will be approximately 200 with participation from theUnited States, Europe and the Pacific Rim in approximately equal proportions.