SBIR Phase I: The Production of Silicon Esters With An Advanced Enzymatic Reactor Technology

SBIR 第一阶段：利用先进的酶反应器技术生产硅酯

• 批准号: 0232780
• 负责人: Fangxiao Yang
• 金额: $ 10万
• 依托单位: RESODYN CORPORATION
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-01-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0232780&HistoricalAwards=false
• 关键词: SBIR; Phase; Production; Silicon; Esters

This Small Business Innovation Research Phase I project will demonstrate the feasibility of an innovative, environmentally benign, enzymatic catalyst process and an advanced reactor design for the production of silicon esters from various feedstocks. All current processes for making silicon esters are either using expensive rare earth metal as catalysts or using halogen elements containing compounds as starting materials and high temperature. Some of them involve using or generating HCl gas and the formation of complex mixtures, which cannot be readily separated. The Phase I objective is to demonstrate feasibility of using immobilized enzyme as a catalyst for silicon ester synthesis coupled with the sonic-enhanced packed bed reactor technology. The investigation will focus on esterification reactions between alkyl silanols and saturated or unsaturated carboxylic acids to produce silicon esters with designed degree of saturation. This enzymatic process will produce both saturated and unsaturated silicon esters that can be used for a broad range of applications, that include repellent coatings, contact lenses, electrical assemblies, perfumes, dyes, brake fluid, chromatography equipment, rubber products, products to reattach detached retinas and more. The unsaturated esters can also be used as monomers for silicon containing polymer production.

这个小企业创新研究第一阶段项目将展示一种创新的、环境友好的酶催化剂工艺和先进的反应器设计的可行性，用于从各种原料生产硅酯。目前制备硅酯的所有方法要么使用昂贵的稀土金属作为催化剂，要么使用含卤素元素的化合物作为起始原料和高温。其中一些涉及使用或产生HCl气体，并形成复杂的混合物，这些混合物不易分离。第一阶段的目标是证明使用固定化酶作为硅酯合成的催化剂与超声增强填充床反应器技术相结合的可行性。本论文主要研究烷基硅醇与饱和或不饱和羧酸的酯化反应，制备具有设计饱和度的硅酯。 这种酶促过程将产生饱和和不饱和硅酯，可用于广泛的应用，包括防水涂料，隐形眼镜，电气组件，香水，染料，制动液，色谱设备，橡胶产品，产品重新连接脱落的视网膜等。不饱和酯也可用作含硅聚合物生产的单体。