NIH-NSF BBSI: Virginia Commonwealth University

建议没有。项目编号：0234101主要研究人员：Gregory buck机构名称：弗吉尼亚联邦大学标题：美国国立卫生研究院-国家科学基金会弗吉尼亚联邦大学BBSI摘要建议申请资助。该提案被专家组评为高度推荐（FUND），项目主管同意专家组的判断。下文概述了有关审查标准的建议的具体意见。随着技术的进步，生物工程和生物信息学领域正在被重新定义，但很明显，最关键的工作将发生在经典学科之间的交叉点。因此，有必要吸引新人进入这个领域，他们在灰色地带工作得很好，并且能够轻松地学会适应分子生物学、计算和数学科学以及工程学的不同语言。VCU团队开发了一个综合课程，以提供在生物信息学和生物工程两个领域的曝光和经验。该研究所符合VCU的总体目标。他们开设了一个新的五年制生物信息学硕士学位，有三个方向：计算与工程、基因组学与生物学、定量与统计。新成立的工程学院重点关注生物工程，并与VCU卫生系统的MCV医院有联系。VCU生命科学公司为这些实体创建了一个保护伞，以加强两个领域的整合。更广泛的影响为了让没有必要的实验室经验的初出苗头的大三学生意识到他们是一个科学项目的积极和有价值的成员，研究所将引导他们通过一系列高度集成的密集研究模拟，灵感来自每个主办实验室的实际问题。计算和数学方法等核心技能基础将有助于跨学科和研究领域整合研究所参与者的分析和方法技能。第一个夏天将为学生提供生物工程和生物信息学的观点，重点关注研究所实验室解决的问题，第二个夏天将提供更广泛的领域。我建议为这项提议提供四年共660 602美元的经费。

PROPOSAL NO.: 0234101PRINCIPAL INVESTIGATOR: Gregory BuckINSTITUTION NAME: Virginia Commonwealth UniversityTITLE: NIH-NSF BBSI at Virginia Commonwealth UniversityAbstractThis proposal is recommended for funding. The proposal was rated as Highly Recommended (FUND) by the panel and the program director agrees with the panel's judgment.Specific comments about the proposal in relation to the review criteria are outlined below.Intellectual MeritThe fields of bioengineering and bioinformatics are being redefined through technological advances, but it is clear that the most critical work will take place at the interface between classical disciplines. It is therefore essential to attract new people to the field who work well in the gray areas and who can learn to adapt easily to the different languages of molecular biology, computational and mathematical sciences, and engineering.The VCU team has developed an integrated curriculum to provide exposure and experiences in both fields of bioinformatics and bioengineering. This Institute fits into the overall goals of VCU. They have developed a new five year Master's in bioinformatics, with three tracks: computational and engineering, genomics and biology, and quantitative and statistical. Newly created School of Engineering has a strong focus in Bioengineering with connection to MCV Hospitals of VCU Health Systems. VCU Life Sciences creates an umbrella over these entities to enhance the integration of the two fields. Broader ImpactIn order to take rising juniors with no necessary laboratory experience and evoke within them the sense that they are active and valuable members of a scientific project, the Institute will lead them through a series of highly integrated intensive research simulations, inspired by actual problems from each of their host laboratories. Core skill bases such as computational and mathematical methods will serve to integrate, across disciplines and research areas, the analytical and methodological skills of the Institute participants. While the first summer will provide students with a view of bioengineering and bioinformatics that is focused on the problems addressed by the laboratories of the institute, the second summer will offer a broader look at the fields.I recommend funding of the proposal for a total of $660,602 for four years.