Acquisition of Radioanalytic Imager

申请资金用于购买BetaScope 603 放射性分析成像仪，用于检测、记录和分析B射线发射 来自任何一维或二维样品的同位素（32 P、35 S、14 C） (gels印迹、TLC板等）。 研究项目包括 蛋白质-核酸生物物理学 相互作用; 2）真核生物和 原核遗传物质; 3）附加体生物学， 转座因子; 4）RNA的生物学和生物化学 真核生物中的加工; 5）核酶的生物化学（即， I组自催化内含子）; 6）生物化学和遗传学 胆固醇和胆汁酸代谢; 7）一类新的MHC 连锁基因和蛋白质产物; 8）因子指导 几类终末分化的 哺乳动物细胞 一群“小用户”研究范围广 生物学问题也被描述。

Funds are requested for an acquisition of the BetaScope 603 Radioanalytic Imager to detect, record and analyze B-emmitting isotopes (32P, 35S, 14C) from any one or two dimensional samples (gels, blots, TLC plates, etc.). Research projects include studies of: 1) the biophysics of protein-nucleic acid interactions; 2) expression and regulation of eukaryotic and prokaryotic genetic material; 3) biology of episomes and transposable elements; 4) the biology and biochemistry of RNA processing in eukaryotes; 5) the biochemistry of ribozymes (i.e., Group I autocatalytic introns); 6) the biochemistry and genetic of cholesterol and bile acid metabolism; 7) a new class of MHC linked genes and protein products; 8) factors directing the development of several classes of terminally differentiated mammalian cell. A group of "minor users" studying a wide range of biological problems is also described.