Acquisition of a Lifetime Spectrofluorometer

购买终身可用的分光荧光计

• 批准号: 0234537
• 负责人: David McFadden
• 金额: $ 11万
• 依托单位: Boston College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-01 至 2006-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0234537&HistoricalAwards=false
• 关键词: Acquisition; Lifetime; Spectrofluorometer

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Boston College will acquire a Spectrofluorometer with Lifetime Capability. This equipment will enhance research focused on biomolecules, biomimetic probes and compounds, and novel materials. Some specific projects include a) characterization of materials used for multiphoton optical memory; b) molecular sensors for DNA damage detection; c) DNA-fluorophore conjugates; d) development of efficient reactions for stereoselective organic synthesis; e) interactions of phospholipases with interfaces; and f) allosteric control of metabolic pathways. Investigators at several institutions in the Boston area will also use the spectrofluorometer. The fluorescence spectrometer counts photons of light in the ultraviolet (UV) and visible regions. When a sample of material is illuminated by UV light at a given frequency or energy, the reflected light consists of the original UV light, but also may contain light in the visible region of the spectrum, at a lower frequency or energy. The fluorometer is a very sensitive instrument used to detect the fluorescence signal.

有了化学研究仪器和设施（CRIF）计划的这一奖项，波士顿学院化学系将获得具有终身能力的荧光分光光度计。该设备将加强对生物分子、仿生探针和化合物以及新型材料的研究。 一些具体项目包括：（a）鉴定用于多光子光学存储器的材料;（B）检测DNA损伤的分子传感器;（c）DNA荧光团结合物;（d）开发立体选择性有机合成的有效反应;（e）磷脂酶与界面的相互作用;（f）代谢途径的变构控制。 波士顿地区几个机构的研究人员也将使用荧光分光光度计。 荧光光谱仪对紫外（UV）和可见光区域中的光子进行计数。当材料样品被给定频率或能量的UV光照射时，反射光由原始UV光组成，但也可能包含光谱的可见光区域中的较低频率或能量的光。荧光计是用于检测荧光信号的非常灵敏的仪器。