CAREER: New Stoichiometric and Catalytic Metal-Mediated Reactions

职业：新化学计量和催化金属介导的反应

• 批准号: 0237249
• 负责人: Paul Chirik
• 金额: --
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Continuing grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0237249&HistoricalAwards=false
• 关键词: CAREER; New; Stoichiometric; Catalytic; Metal

This CAREER award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research and educational activities in chemical synthesis by Professor Paul Chirik and his research group in the Department of Chemistry and Chemical Biology at Cornell University. The goal of the research is to develop transition metal reagents to induce reactivity in otherwise inert molecules. Professor Chirik and coworkers are particularly interested in learning how the environment around the metal center can be manipulated to induce reactivity with elemental nitrogen, phosphorus and aliphatic carbon-carbon bonds. Ultimately, these studies may allow construction of new pharmaceuticals and other commodity and specialty chemicals from underutilized natural resources. Educational activities connected with this research are designed to demonstrate the vital role chemical synthesis plays in modern society. These concepts will be presented as part of an introductory chemistry course for engineers, a graduate course for first year students, as well as in community programs designed to reach children and adults in the local area.This research strives to fix elemental nitrogen, which can be derived from air, and elemental phosphorous, directly into organic molecules through new methods that could lead to more energy efficient industrial processes. Educational activities will be developed to demonstrate to students both in higher education and in the surrounding community the vital role that chemical synthesis plays in modern society.

无机，生物无机和有机化学计划的职业奖支持保罗·奇里克教授及其在康奈尔大学化学和化学生物学系的研究小组在化学合成方面的研究和教育活动。 该研究的目标是开发过渡金属试剂，以诱导其他惰性分子的反应性。 Chirik教授和同事们特别感兴趣的是如何操纵金属中心周围的环境，以诱导与元素氮，磷和脂肪族碳-碳键的反应。 最终，这些研究可能允许从未充分利用的自然资源中构建新的药品和其他商品和特种化学品。 与这项研究有关的教育活动旨在展示化学合成在现代社会中的重要作用。 这些概念将作为工程师化学入门课程的一部分，一年级学生的研究生课程，以及旨在接触当地儿童和成人的社区项目的一部分。这项研究致力于通过新方法将元素氮（可以从空气中提取）和元素磷直接固定到有机分子中，从而实现更节能的工业过程。将开展教育活动，向高等教育和周边社区的学生展示化学合成在现代社会中的重要作用。