SBIR Phase II: ECR (Electron Cyclotron Resonance) Plasma Treatment of Polymer Tubing Such As Catheters

这个小型企业创新研究(SBIR)第二阶段项目将开发新的技术来处理聚合物管的内外表面，如导管。这些处理将对表面进行改性，以促进生物活性涂层的附着、清洁、杀菌或减少摩擦；类似的工艺也可以沉积有机或无机涂层。由电子回旋共振(ECR)驱动的等离子体将比传统等离子体更均匀地处理管腔和外表面，并在更大的参数范围内处理，并且可以在空间上定位以对每个表面提供不同的效果。ECR等离子体技术应该可以扩展到大规模、低成本的商业生产中，用于导管的涂层和表面改性。表面处理有助于将生物活性涂层附着到血液透析和其他类型的导管上，通过延长导管更换之间的时间间隔将产生社会效益，具有明确的治疗效果和经济价值。

This Small Business Innovation Research (SBIR) Phase II project will develop new techniques to treat both internal and external surfaces of polymer tubing such as catheters. The treatments will modify the surfaces to facilitate attachment of bioactive coatings, clean, sterilize, or reduce friction; similar processes can also deposit organic or inorganic coatings. Plasmas driven by electron cyclotron resonance (ECR) will treat the lumen and external surfaces more uniformly, and over a greater range of parameters, than conventional plasmas and can be spatially localized to provide different effects on each. The ECR plasma process should be expandable to large-scale, low-cost commercial production coating and surface modification of catheters. Surface treatments to facilitate attachment of bioactive coatings to hemodialysis and other catheter types would have societal benefits by extending the period between catheter replacements clear therapeutic and economic.