Functions of the cGMP-dependent protein kinase (PKG) in honey bee division of labor

cGMP依赖性蛋白激酶（PKG）在蜜蜂分工中的功能

• 批准号: 162373540
• 负责人: Professorin Dr. Ricarda Scheiner-Pietsch
• 金额: --
• 依托单位: Lehrstuhl für Verhaltensphysiologie und Soziobiologie (Zoologie II)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2010
• 资助国家: 德国
• 起止时间: 2009-12-31 至 2015-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/162373540?language=en
• 关键词: Functions; cGMP; dependent; protein; kinase

The aim of this proposal is to understand the functions of the cGMP-dependent protein kinase (PKG) in honey bee division of labor. In particular, we want to answer the following questions:milestone 1: what is the relationship between the amount of PKG, PKG activity, gustatory responsiveness, satiation and age-dependent division of labor in honey bees?milestone 2: how is the PKG activated in the brain?milestone 3: which are the cellular targets of PKG phosphorylation?

本研究的目的是了解cGMP依赖的蛋白激酶(PKG)在蜜蜂分工中的作用。具体来说，我们想要回答以下问题：里程碑1：蜜蜂体内PKG的数量、PKG活性、味觉反应性、饱腹感与年龄相关的劳动分工之间的关系是什么？里程碑2：PKG是如何在大脑中激活的？里程碑3：PKG磷酸化的细胞靶点是什么？