Stem cell-based interface tissue engineering

基于干细胞的界面组织工程

• 批准号: DP0986619
• 负责人: Prof Justin Cooper-White
• 金额: $ 9.52万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2010-04-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0986619
• 关键词: Stem; cell; based; interface; tissue

Osteoarthritis (OA) causes extreme pain, disability, and reduced quality of life and overall productivity. It is the musculoskeletal disorder with the greatest social and economic implications internationally, with 9.3% of the adult population projected to suffer from OA by 2030. A tissue engineered product capable of functional repair of ligament-cartilage-bone tissue interfaces will have significant benefits. It will improve patient activity and quality of life, and significantly reduce OA-associated health care costs. This proposal will train a total of 12 new generation researchers in the emergent fields of stem cell biology and tissue engineering, having important benefits for the Australian scientific and industrial communities.

骨关节炎（OA）导致极度疼痛、残疾、生活质量下降和整体生产力下降。它是国际上具有最大社会和经济影响的肌肉骨骼疾病，预计到2030年将有9.3%的成年人口患有OA。能够功能性修复韧带-软骨-骨组织界面的组织工程产品将具有显著的益处。它将改善患者的活动和生活质量，并显着降低OA相关的医疗保健成本。该计划将在干细胞生物学和组织工程等新兴领域培养12名新一代研究人员，对澳大利亚科学和工业界具有重要意义。