NMR Spectroscopy as a Cornerstone Technique in the Undergraduate Chemical Curriculum

核磁共振波谱作为本科化学课程的基石技术

• 批准号: 0310901
• 负责人: Kevin Shaughnessy
• 金额: $ 12.07万
• 依托单位: University of Alabama Tuscaloosa
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0310901&HistoricalAwards=false
• 关键词: NMR; Spectroscopy; Cornerstone; Technique; Undergraduate

Chemistry (12) Nuclear Magnetic Resonance (NMR) is a powerful technique for structural determination and quantification that is widely used across all areas of science. In the traditional undergraduate curriculum, hands-on experience with NMR is typically limited outside of sophomore organic classes. This project uses NMR as a cornerstone technique in nine undergraduate laboratory classes. In additional to traditional uses of NMR to identify and characterize structures in organic and inorganic chemistry, NMR is being used to demonstrate principles in analytical, physical chemistry, and biochemistry labs. The specific goal of this project is to improve student understanding of chemical principles, by using NMR as a cornerstone technique, with which students become proficient over their career. To achieve our goals of expanding NMR beyond the sophomore organic lab, we are using a modern, high-field NMR spectrometer. The new instrument is used in a hands-on fashion by both chemistry majors and non-majors taking sophomore through senior level chemistry lab classes. Published experiments, primarily from the Journal of Chemical Education, are being adapted and integrated within the nine courses in order to achieve our curricular goals. A tutorial page is used to walk students through the transfer and processing of a standard NMR data file, with the processing system modeled on one used at Florida State University. Finally, a workshop is being offered annually to regional four-year institutions that are interested in having student samples run on our NMR. The results are e-mailed back to the students who then use software capable of all standard NMR processing functions to analyze their data.Intellectual Merit: The use of technology in the classroom is of increasing importance to teach modern scientific concepts and engage computer literate students. NMR is a central technique since it can be used to study a variety of problems. This project is leading to the development of a number of new laboratory experiments, and these experiments will be made available to other instructors interested in increasing the use of NMR in their laboratory classes. Broader Impact: The proposed project is involving approximately 300 undergraduate students per year. These students receive hands-on experience as a means to learn fundamental chemical concepts. We also expect that students will be excited about chemistry, and science in general, as a result of this project. In particular, by reaching out to non-majors we hope to encourage these students, particularly those from under-represented groups, to consider careers in the sciences.

化学 (12) 核磁共振 (NMR) 是一种强大的结构测定和定量技术，广泛应用于所有科学领域。 在传统的本科课程中，核磁共振的实践经验通常仅限于大二有机课程之外。 该项目在九个本科生实验室课程中使用核磁共振作为基础技术。 除了传统使用 NMR 来识别和表征有机和无机化学中的结构外，NMR 还用于演示分析、物理化学和生物化学实验室的原理。 该项目的具体目标是通过使用核磁共振作为基础技术，提高学生对化学原理的理解，使学生在其职业生涯中变得熟练。 为了实现将 NMR 扩展到二年级有机实验室之外的目标，我们正在使用现代化的高场 NMR 波谱仪。化学专业的学生和非专业学生从二年级到高级化学实验室课程都可以实际使用这种新仪器。 主要来自《化学教育杂志》的已发表实验正在被改编并整合到九门课程中，以实现我们的课程目标。 教程页面用于引导学生完成标准 NMR 数据文件的传输和处理，处理系统以佛罗里达州立大学使用的系统为模型。 最后，每年都会向有兴趣在我们的 NMR 上运行学生样本的地区四年制机构举办一次研讨会。 结果通过电子邮件发回给学生，然后学生使用具有所有标准 NMR 处理功能的软件来分析他们的数据。 智力优势：在课堂上使用技术对于教授现代科学概念和吸引具有计算机知识的学生越来越重要。 核磁共振是一项核心技术，因为它可用于研究各种问题。 该项目正在开发许多新的实验室实验，这些实验将提供给有兴趣在实验室课程中增加 NMR 使用的其他教师。更广泛的影响：拟议项目每年涉及约 300 名本科生。 这些学生获得实践经验，作为学习基本化学概念的手段。 我们还希望通过这个项目，学生们会对化学和一般科学感到兴奋。 特别是，通过接触非专业学生，我们希望鼓励这些学生，特别是来自代表性不足群体的学生，考虑从事科学事业。