RUI: Supramolecular Utility of a Versatile New Electron Acceptor

在化学系有机动力学项目的支持下，霍利奥克山学院的达伦汉密尔顿教授将继续进行一项研究计划，该计划专门围绕苯六酸三酰亚胺的合成和物理化学，这是PI实验室开发的一类新的电子受体，并于2001年首次发表。一个重要的研究计划计划的基础上观察到，这些新的三酰亚胺可以归类，结构和功能，与苯，萘，和二萘嵌苯的二酰亚胺。这些结构已经受到了极大的关注，主要是由于它们的强电子接受性质。它们在超分子化学的许多研究领域的发展中发挥了关键作用，涉及的领域包括拓扑结构和分子尺度机械，电子材料，氧化还原活性生物辅因子的模拟物，DNA intercolators和传感器。提出的研究计划的首要目标是充分引入新的三酰亚胺积木到这个多样化的竞技场，通过展示可行的核心访问，并表征其衍生物和可能产生的分子组装的紧急属性。基于三酰亚胺平台的研究项目将为本科生提供刺激和多样的实验室体验，涉及合成，光谱和材料表征。这项工作将使参与者对不断扩大的当代研究领域有一个重要的了解，并将有助于霍利奥克山学院化学的强大传统。有机和高分子化学计划支持教授达伦汉密尔顿在山霍利奥克学院谁计划在本科生学院广泛影响基于研究的奖学金的两个关键要素。首先，通过包括既展示重要概念又为更大的研究计划提供使用材料的模块来活跃所有学生所采取的实验序列。第二，在大学生涯的早期，尝试识别和鼓励那些以前没有考虑过参与研究的可能性或不愿意向前迈进的学生。利用这种接触机制，将鼓励女本科生考虑通过参加暑期项目或通过监督下的独立研究来参与研究项目的问题。十年前，美国四分之一的女性化学家毕业于霍利奥克山学院，该学院仍然是女性博士化学家最多产的来源之一。

With the support of the Organic Dynamics Program in the Chemistry Division, Professors Darren Hamilton at Mount Holyoke College will continue a research program that is built exclusively around the synthetic and physical chemistry of mellitic triimides, a new class of electron acceptors developed in the PI's laboratory and published for the first time in 2001. A significant program of study is planned based the observation that these new triimides may be classed, structurally and functionally, with the diimides of benzene, naphthalene, and perylene. These structures have received a great deal of attention, principally due to their strongly electron accepting nature. They have played key roles in the development of numerous areas of investigation in supramolecular chemistry, involving areas such as topology and molecular scale machinery, electronic materials, mimics of redox active biological co-factors, DNA intercolators, and sensors. The overarching aim of the program of study proposed is to fully introduce the new triimide building block to this diverse arena by demonstrating viable access to the core, and characterizing emergent properties in its derivatives and the molecular assemblies that may result. Research projects based on the triimide platform will provide stimulating and varied laboratory experiences for undergraduates that will involve synthesis, spectroscopy, and materials characterization. The work will give participants an important glimpse of an expanding contemporary area of research inquiry, and will contribute to the strong tradition of preparation that characterizes chemistry at Mount Holyoke College..The Organic and Macromolecular Chemistry Program supports Professor Darren Hamilton at Mount Holyoke College who plans to broadly impact two key elements of research-based scholarship in an undergraduate college. First, to enliven the experimental sequence taken by all students by including modules that both demonstrate important concepts and provide materials of use to the larger research program. Second, to attempt to identify and encourage students early in their college careers who have not previously considered the possibility of involvement in research, or who have been reluctant to step forward. Using this mechanism of exposure, female undergraduates will be encouraged to consider the question of their involvement with a research program, through participation in a summer program, or through supervised independent study. As of a decade ago, one in four women chemists in the US graduated from Mount Holyoke College, and the college remains one of the most productive sources of women PhD chemists.