MRI: Acquisition of Equipment for a Microgenomics Facility

MRI:为微观基因组学设施购置设备

基本信息

  • 批准号:
    0320858
  • 负责人:
  • 金额:
    $ 25.83万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2003
  • 资助国家:
    美国
  • 起止时间:
    2003-07-01 至 2006-06-30
  • 项目状态:
    已结题

项目摘要

A grant has been awarded to Kent State University under the direction of Dr. Mintz for the purchase of two instruments dedicated to measuring cell-specific gene expression. The first instrument is a laser capture microscope, which allows researchers to extract individual cells or groups of cells from tissues in order to analyze their contents. The second instrument is an Affymetrix GeneChip instrument system, which will allow researchers to analyze the expression patterns of thousands of genes simultaneously from just a few cells extracted using the laser capture microscope. With these instruments, researchers can examine differences in gene activity between different types of cells that are all mixed together in one tissue. This is of critical importance in understanding how individual cells serve different roles within one tissue.Many projects at Kent State in diverse areas of the life sciences will benefit from this instrumentation. Although these instruments are often used in genetic and molecular biology studies, we seek mainly to apply their power to ask questions in the areas of neuroendocrinology, reproductive physiology, environmental biology, and biochemistry. The Kent State Department of Biological Sciences has an ongoing collaboration with the departments of Physics, Mathematics, and Computer Science in the fields of computational neuroscience and bioinformatics, and these instruments will add many new possible directions for that collaboration.In addition to the benefits to Kent State's research programs, this instrumentation will have a significant impact on the educational experience we can give our students. Experience with this modern equipment through individual research mentoring by faculty will strongly benefit both our graduate and undergraduate students, and significantly enhance their ability to obtain positions after completing their educations. In addition, the instrumentation will be incorporated into our summer cell and molecular biology workshop, used specifically to give formal training in techniques to interested students. Overall, this award will enhance the scientific productivity of both faculty and students at Kent State University and support new and exciting directions in research.
在明茨博士的指导下,肯特州立大学获得了一笔赠款,用于购买两台专门用于测量细胞特异性基因表达的仪器。第一种仪器是激光捕获显微镜,它允许研究人员从组织中提取单个或一组细胞,以分析其内容物。第二个仪器是Affymetrix基因芯片仪器系统,它将允许研究人员从使用激光捕获显微镜提取的几个细胞中同时分析数千个基因的表达模式。使用这些仪器,研究人员可以检查混合在一个组织中的不同类型细胞之间的基因活性差异。这对于理解单个细胞如何在一个组织中扮演不同的角色至关重要。肯特州立大学生命科学不同领域的许多项目都将从这一仪器中受益。虽然这些仪器经常用于遗传和分子生物学研究,但我们主要寻求利用它们的力量在神经内分泌学、生殖生理学、环境生物学和生物化学领域提出问题。肯特州立大学生物科学部与物理、数学和计算机科学系在计算神经科学和生物信息学领域正在进行合作,这些仪器将为这种合作增加许多新的可能方向。除了为肯特州立大学的研究计划带来好处外,这种仪器还将对我们可以给我们的学生提供的教育体验产生重大影响。通过教师的个人研究指导使用这种现代化设备的经验将使我们的研究生和本科生受益匪浅,并显著提高他们完成学业后获得工作的能力。此外,仪器将被纳入我们的暑期细胞和分子生物学工作坊,专门用于为感兴趣的学生提供正式的技术培训。总体而言,该奖项将提高肯特州立大学教职员工和学生的科学生产率,并支持新的和令人兴奋的研究方向。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Eric Mintz其他文献

Correction to: A large and persistent outbreak of typhoid fever caused by consuming contaminated water and street-vended beverages: Kampala, Uganda, January – June 2015
  • DOI:
    10.1186/s12889-017-4801-y
  • 发表时间:
    2017-10-18
  • 期刊:
  • 影响因子:
    3.600
  • 作者:
    Steven Ndugwa Kabwama;Lilian Bulage;Fred Nsubuga;Gerald Pande;David Were Oguttu;Richardson Mafigiri;Christine Kihembo;Benon Kwesiga;Ben Masiira;Allen Eva Okullo;Henry Kajumbula;Joseph KB Matovu;Issa Makumbi;Milton Wetaka;Sam Kasozi;Simon Kyazze;Melissa Dahlke;Peter Hughes;Juliet Nsimire Sendagala;Monica Musenero;Immaculate Nabukenya;Vincent R. Hill;Eric Mintz;Janell Routh;Gerardo Gómez;Amelia Bicknese;Bao-Ping Zhu
  • 通讯作者:
    Bao-Ping Zhu

Eric Mintz的其他文献

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{{ truncateString('Eric Mintz', 18)}}的其他基金

Implementation Project: Data Driven, Engagement Based, Adaptive Learning, Growth Mindset Pedagogy Informed Course Redesign with Early Research Experiences for STEM Student Success
实施项目:数据驱动、基于参与、适应性学习、成长心态教育学的课程重新设计以及 STEM 学生成功的早期研究经验
  • 批准号:
    1912256
  • 财政年份:
    2019
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Continuing Grant
Data Driven, Engagement Based, Adaptive Learning, Growth Mindset Pedagogy Informed Course Redesign with Early Research Experiences for STEM Student Success
数据驱动、基于参与、适应性学习、成长心态教学法以及早期研究经验的课程重新设计,促进 STEM 学生的成功
  • 批准号:
    1818682
  • 财政年份:
    2018
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Standard Grant
Building CAU Capacity to Prepare STEM Teachers for High Need K-12 School Districts
建设中国农业大学为高需求 K-12 学区培养 STEM 教师的能力
  • 批准号:
    1340039
  • 财政年份:
    2013
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Standard Grant
Spatial and Temporal Mapping of the Suprachiasmatic Nucleus Transcriptome
视交叉上核转录组的时空作图
  • 批准号:
    1021957
  • 财政年份:
    2010
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Continuing Grant
Renovation of the Biology Building Into The Environmental Sciences Research Laboratory
生物楼改造为环境科学研究实验室
  • 批准号:
    9214451
  • 财政年份:
    1995
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Standard Grant
Thermal Analysis System for Characterization and Evaluation of High Performance Polymers & Ceramics
用于高性能聚合物表征和评估的热分析系统
  • 批准号:
    9253016
  • 财政年份:
    1992
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Standard Grant
Investigation of Bridged Organometallic Complexes on Metal Oxide Supports
金属氧化物载体上桥联有机金属配合物的研究
  • 批准号:
    9014260
  • 财政年份:
    1990
  • 资助金额:
    $ 25.83万
  • 项目类别:
    Standard Grant

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