Enhancing Capacity for Molecular and Evolutionary Genetic Research at The University of Montana: Acquisition of a Genetic Analyzer and Related Equipment

增强蒙大拿大学分子和进化遗传学研究能力：购置遗传分析仪和相关设备

• 批准号: 0321329
• 负责人: Lila Fishman
• 金额: --
• 依托单位: University of Montana
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0321329&HistoricalAwards=false
• 关键词: Enhancing; Capacity; Molecular; Evolutionary; Genetic

A grant has been awarded to the University of Montana under the direction of Dr. L.Fishman, Dr. S. Miller, Dr. M. Minnick and Dr. R. Rosenzweig for the purchase of instrumentation to support research in evolutionary and molecular genetics in the Division of Biological Sciences (DBS) and the School of Forestry at UM. This instrumentation will increase the speed, efficiency and affordability of DNAsequencing, genotyping and gene expression analysis in order to reveal the connections between genotype and phenotype, and to understand how changes in DNA sequence and gene expression contribute to divergent evolution. The requested instrumentation will benefit the research programs of at least twelve faculty working in fields from Conservation Biology to Insect Evolution and Development to Viral Evolution. The research activities of the core users include ecological genetics of floral evolution and development of postzygotic isolating mechanisms in flowering plants, molecular phylogenetics of cyanobacteria, and evolutionary functional genomics of yeast. The equipment purchases will simultaneously invigorate all research activities at the University of Montana that utilize DNA analyses. The requested instrumentation will also advance UM's educational goals through use in established training and outreach programs, as well as increased opportunities for cutting-edge student research. Enhanced molecular genetic instrumentation will further the goal of providing research opportunities for undergraduate students, both in individual labs and as a component of DBS's core curriculum. The proposed equipment will also facilitate the execution of ambitious pre- and post-doctoral research projects and will prepare young researchers to succeed in the rapidly changing environment of biology research.

在L·菲什曼博士、S·米勒博士、M·明尼克博士和R·罗森茨韦格博士的指导下，蒙大拿大学获得了一笔赠款，用于购买仪器，以支持生物科学部(DBS)和密歇根大学林业学院的进化和分子遗传学研究。这一仪器将提高DNA测序、基因分型和基因表达分析的速度、效率和可负担性，以揭示基因和表型之间的联系，并了解DNA序列和基因表达的变化如何有助于差异进化。所要求的仪器将使从保护生物学到昆虫进化和发育再到病毒进化等领域的至少12名教员的研究计划受益。核心用户的研究活动包括开花植物花的进化和合子后分离机制的生态遗传学、蓝藻的分子系统发育和酵母的进化功能基因组学。设备采购将同时为蒙大拿大学利用DNA分析的所有研究活动注入活力。所要求的工具还将通过在既定的培训和推广计划中使用以及增加尖端学生研究的机会来促进密歇根大学的教育目标。增强的分子遗传学仪器将进一步实现为本科生提供研究机会的目标，无论是在个人实验室还是作为星展银行核心课程的一部分。拟议的设备还将促进执行雄心勃勃的博士后和博士后研究项目，并将为年轻研究人员在迅速变化的生物学研究环境中取得成功做好准备。