The Integration of Liquid- and Solid-State NMR into the Undergraduate Physical Chemistry Curriculum

液态和固态核磁共振融入本科物理化学课程

• 批准号: 0341487
• 负责人: Karl Mueller
• 金额: $ 7.5万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0341487&HistoricalAwards=false
• 关键词: Integration; Liquid; Solid; State; NMR

This project addresses issues of fundamental reform in the physical chemistry curriculum via advanced integration of liquid- and solid-state nuclear magnetic resonance (NMR) experiments. A comprehensive suite of NMR laboratory exercises (initially targeted within the physical chemistry laboratory) builds in level of sophistication from simple liquid-state measurements through static, magic-angle spinning (MAS), and cross-polarization MAS solid-state experiments. Alone, or in concert, these experiments provide multiple layers of instructional merit from basic structural characterization to important physical chemistry concepts. Since not all instructional programs have solid-state NMR capabilities, we develop and market schematics and construction materials for a low-cost ($2500) static 2H probe that is compatible with existing liquid-state spectrometers. Deuterium NMR line shapes are sensitive to molecular motion and serve as excellent instructional aids for topics such as methyl rotors. For educational materials we include fully supported multimedia presentations of the basic concepts of liquid- and solid-state NMR and complete step-by-step instructions for each experimental exercise. We use the assessment strategies developed and supported by the Penn State Center for Excellence in Learning and Teaching to gauge the strengths and weaknesses of these tools. In terms of intellectually merited outcomes, we provide an integrated series of authentic experiences, using NMR as a unifying theme, connecting theory, concepts, and research. More broadly, tools are designed for vertical integration into organic and instrumental analysis courses at PSU. Additionally, during this initial phase, we seek partner institutions to implement the material during future full-scale development.

本计画探讨物理化学课程之基础性改革议题，透过液态与固态核磁共振实验之先进整合。一套全面的NMR实验室练习（最初针对物理化学实验室）建立在复杂的水平，从简单的液态测量到静态，魔角旋转（MAS）和交叉极化MAS固态实验。单独或协同，这些实验提供了从基本结构表征到重要物理化学概念的多层次教学价值。由于并非所有的教学计划都具有固态NMR功能，因此我们开发和销售低成本（2500美元）静态2H探针的原理图和建筑材料，该探针与现有的液态光谱仪兼容。氘核磁共振谱线的形状对分子运动很敏感，可以作为甲基转子等主题的优秀教学辅助工具。对于教育材料，我们包括液体和固体NMR基本概念的完全支持的多媒体演示，以及每个实验练习的完整分步说明。我们使用宾夕法尼亚州立大学卓越学习和教学中心开发和支持的评估策略来衡量这些工具的优点和缺点。就智力上值得的成果而言，我们提供一系列完整的真实体验，使用核磁共振作为统一主题，将理论、概念和研究联系起来。更广泛地说，工具是专为垂直整合到有机和仪器分析课程在PSU。此外，在这个初始阶段，我们寻求合作伙伴机构在未来的全面发展中实施材料。