The Integration of Liquid- and Solid-State NMR into the Undergraduate Physical Chemistry Curriculum

本项目旨在通过液态核磁共振与固态核磁共振实验的先进整合，解决物理化学课程的根本性改革问题。一套全面的核磁共振实验室练习（最初是在物理化学实验室中进行的）建立了从简单的液态测量到静态、魔角旋转（MAS）和交叉极化MAS固态实验的复杂程度。这些实验单独或协同提供了从基本结构表征到重要物理化学概念的多层教学价值。由于并非所有的教学程序都具有固态核磁共振功能，我们开发和销售低成本（2500美元）静态2H探针的原理图和建筑材料，该探针与现有的液态光谱仪兼容。氘核磁共振线的形状是敏感的分子运动，并作为极好的教学辅助主题，如甲基转子。对于教育材料，我们包括完全支持的液体和固态核磁共振的基本概念的多媒体演示，并为每个实验练习完成一步一步的说明。我们使用宾夕法尼亚州立大学卓越学习与教学中心开发和支持的评估策略来衡量这些工具的优缺点。就智力成果而言，我们提供了一系列完整的真实体验，使用NMR作为统一的主题，连接理论，概念和研究。更广泛地说，工具的设计是为了垂直整合到PSU的有机和仪器分析课程中。此外，在这个初始阶段，我们寻求合作机构在未来的全面发展中实施这些材料。

This project addresses issues of fundamental reform in the physical chemistry curriculum via advanced integration of liquid- and solid-state nuclear magnetic resonance (NMR) experiments. A comprehensive suite of NMR laboratory exercises (initially targeted within the physical chemistry laboratory) builds in level of sophistication from simple liquid-state measurements through static, magic-angle spinning (MAS), and cross-polarization MAS solid-state experiments. Alone, or in concert, these experiments provide multiple layers of instructional merit from basic structural characterization to important physical chemistry concepts. Since not all instructional programs have solid-state NMR capabilities, we develop and market schematics and construction materials for a low-cost ($2500) static 2H probe that is compatible with existing liquid-state spectrometers. Deuterium NMR line shapes are sensitive to molecular motion and serve as excellent instructional aids for topics such as methyl rotors. For educational materials we include fully supported multimedia presentations of the basic concepts of liquid- and solid-state NMR and complete step-by-step instructions for each experimental exercise. We use the assessment strategies developed and supported by the Penn State Center for Excellence in Learning and Teaching to gauge the strengths and weaknesses of these tools. In terms of intellectually merited outcomes, we provide an integrated series of authentic experiences, using NMR as a unifying theme, connecting theory, concepts, and research. More broadly, tools are designed for vertical integration into organic and instrumental analysis courses at PSU. Additionally, during this initial phase, we seek partner institutions to implement the material during future full-scale development.