The Integration of Liquid- and Solid-State NMR into the Undergraduate Physical Chemistry Curriculum

该项目通过液体和固体核磁共振实验的先进集成来解决物理化学课程的根本性改革问题。一套全面的核磁共振实验室练习(最初以物理化学实验室为目标)从简单的液体测量到静态、魔角旋转(MAS)和交叉极化MAS固态实验，建立了复杂的水平。这些实验单独或协同地提供了从基本结构表征到重要物理化学概念的多层次教学优点。由于并不是所有的教学项目都具有固态核磁共振功能，我们开发并销售与现有液态光谱仪兼容的低成本(2500美元)静态2H探头的原理图和构造材料。氘核磁共振线的形状对分子运动很敏感，是诸如甲基旋转体等主题的极好的教学辅助工具。对于教育材料，我们包括液体和固态核磁共振基本概念的完全支持的多媒体演示，并为每个实验练习提供完整的逐步说明。我们使用由宾夕法尼亚州立大学卓越学习与教学中心开发和支持的评估战略来衡量这些工具的优势和劣势。就智力上值得的结果而言，我们提供了一系列完整的真实经验，使用核磁共振作为统一的主题，将理论、概念和研究联系在一起。更广泛地说，工具是为在PSU的有机和工具分析课程中垂直整合而设计的。此外，在这一初始阶段，我们寻求合作机构在未来全面开发期间实施材料。

This project addresses issues of fundamental reform in the physical chemistry curriculum via advanced integration of liquid- and solid-state nuclear magnetic resonance (NMR) experiments. A comprehensive suite of NMR laboratory exercises (initially targeted within the physical chemistry laboratory) builds in level of sophistication from simple liquid-state measurements through static, magic-angle spinning (MAS), and cross-polarization MAS solid-state experiments. Alone, or in concert, these experiments provide multiple layers of instructional merit from basic structural characterization to important physical chemistry concepts. Since not all instructional programs have solid-state NMR capabilities, we develop and market schematics and construction materials for a low-cost ($2500) static 2H probe that is compatible with existing liquid-state spectrometers. Deuterium NMR line shapes are sensitive to molecular motion and serve as excellent instructional aids for topics such as methyl rotors. For educational materials we include fully supported multimedia presentations of the basic concepts of liquid- and solid-state NMR and complete step-by-step instructions for each experimental exercise. We use the assessment strategies developed and supported by the Penn State Center for Excellence in Learning and Teaching to gauge the strengths and weaknesses of these tools. In terms of intellectually merited outcomes, we provide an integrated series of authentic experiences, using NMR as a unifying theme, connecting theory, concepts, and research. More broadly, tools are designed for vertical integration into organic and instrumental analysis courses at PSU. Additionally, during this initial phase, we seek partner institutions to implement the material during future full-scale development.