CAREER: Theoretical Aspects of Single Molecule Spectroscopy: Control, Tracking, and Unraveling Dynamical Events in the Condensed Phase

职业：单分子光谱学的理论方面：控制、跟踪和揭示凝聚相中的动力学事件

• 批准号: 0344930
• 负责人: J. Eli Barkai
• 金额: $ 51.5万
• 依托单位: University of Notre Dame
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-02-01 至 2006-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0344930&HistoricalAwards=false
• 关键词: CAREER; Theoretical; Aspects; Single; Molecule

Professor J. Eli Barkai of the University of Notre Dame is supported by the Theoretical and Computational Chemistry program through a CAREER award to develop theoretical methods for the treatment of single molecule spectroscopy, a powerful modern technique used to investigate a wide range of physical, chemical and biophysical phenomena. Several applications are being considered: the theory of single photons on demand; anti-bunching behavior for molecular systems in condensed phase environments; non-ergodic blinking of quantum dots; tracking of single molecules in solution; and single macromolecular fluorescence. Barkai is using the quantum jump approach, also called the quantum Monte Carlo approach, to model these systems.As part of this CAREER award, Professor Barkai is developing several courses in theoretical and computational chemistry, one of which is an interdisciplinary course aimed at students from departments beyond Chemistry. In addition, the research will have a broad impact on fields beyond chemistry, especially those of biology and medicine in which single molecule spectroscopy is expected to play a role.

圣母大学的 J. Eli Barkai 教授通过职业奖获得理论和计算化学项目的支持，开发处理单分子光谱的理论方法，这是一种强大的现代技术，用于研究广泛的物理、化学和生物物理现象。 正在考虑几个应用：按需单光子理论；凝聚相环境中分子系统的反聚束行为；量子点的非遍历闪烁；追踪溶液中的单分子；和单一大分子荧光。 Barkai 正在使用量子跳跃方法（也称为量子蒙特卡罗方法）来对这些系统进行建模。作为该职业奖的一部分，Barkai 教授正在开发几门理论和计算化学课程，其中一门是针对化学以外系的学生的跨学科课程。 此外，这项研究还将对化学以外的领域产生广泛影响，特别是单分子光谱学有望发挥作用的生物学和医学领域。