SBIR Phase II: Mouthrinse Generator for Plaque and Halitosis Control

这项小型企业创新研究（SBIR）的第二阶段将开发和商业化电化学操作设备，通过在便携式设备和冲洗器中提供按需生产的漱口水，将彻底改变口腔卫生行业。在这些装置中产生的漱口水将有效控制口臭和牙菌斑，并提供牙齿美白。在第一阶段的研究中，所有建议的目标和指定的成功标准都已完成，以充分证明项目的概念和可行性。在第二阶段，将进一步优化参数，随后将与一家著名的交钥匙制造公司合作设计和制造原型，并在临床环境中测试100台便携式设备。这个项目的商业影响将在口腔卫生产品领域。据估计，多达8500万美国人患有口臭，超过3500万美国人患有牙周病。因此，在这个项目中开发的具有成本效益的设备预计将在47亿美元的口腔护理行业中具有巨大的市场潜力。

This Small Business Innovation Research (SBIR) Phase II will develop and commercialize electrochemically operated devices that will revolutionize the oral hygiene industry by providing an on-demand generation of mouthwash in a portable device and in an irrigator. The mouthwash generated in these devices will be effective in controlling halitosis and dental plaque and will also provide tooth whitening. In the Phase I study, all of the proposed objectives and specified criteria of success were accomplished to amply establish the proof of concept and feasibility of the project. In Phase II, further optimization of the parameters will be followed by the design and fabrication of prototypes in conjunction with a prominent company dealing with turnkey manufacturing, and the testing of 100 portable units in a clinical setting.The commercial impact of this project will be in the area of oral hygiene products. It is broadly estimated that up to 85 million Americans have halitosis, and over 35 million suffer from periodontal disease. Thus, the cost effective devices to be developed in this project are expected to have a large market potential in the $ 4.7 billion oral care industry.