Acquisition of equipment for direct observation of colloid attachment-detachment dynamics and direct measurement of colloid-substratum interaction and adhesion forces

购置直接观察胶体附着-脱离动力学和直接测量胶体-基质相互作用和粘附力的设备

• 批准号: 0352482
• 负责人: William Johnson
• 金额: $ 31.44万
• 依托单位: University of Utah
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-02-15 至 2007-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0352482&HistoricalAwards=false
• 关键词: Acquisition; equipment; direct; observation; colloid

0352482JohnsonThis grant provides partial support for the acquisition of two instruments necessary for direct examination of colloidal attachment-detachment dynamics, and direct determination of colloid and substratum interactions: 1) a system combining a flow cell with total internal reflection fluorescence microscopy and image analysis capability (Flow-TIRFM); and 2) an electrochemical atomic force microscope (AFM) with TIRFM capability. The acquisition will enhance existing research and education projects in colloidal (bacterial) attachment-detachment dynamics in porous media, imaging of intercellular and appendageal molecular transport pathways, identification of structures associated with electron transport across oxide films, and quantification of interaction of macromolecules with inorganic surfaces, protein (or polymer)-surface interactions, and determination of the effects of these interactions on adhesion dynamics with various surfaces. Benefits to society include improved pathogen transport models for determination of rules for groundwater resource protection, improved drug delivery strategies, enhanced composite battery materials, and improved surface preparation technologies.***

0352482约翰逊这笔赠款为购买两台仪器提供部分支持，这两台仪器用于直接检查胶体附着-脱离动力学，以及直接测定胶体与基质的相互作用：1)结合流动池与全内反射荧光显微镜和图像分析能力(FLOW-TIRFM)的系统；以及2)具有TIRFM能力的电化学原子力显微镜(AFM)。这项收购将加强现有的研究和教育项目，这些项目包括：多孔介质中胶体(细菌)附着-脱离动力学、细胞间和附壁分子传输路径的成像、识别与氧化膜之间的电子传输相关的结构、量化大分子与无机表面的相互作用、蛋白质(或聚合物)与表面的相互作用，以及确定这些相互作用对与不同表面的附着动力学的影响。对社会的好处包括改进病原体传输模型，以确定地下水资源保护规则，改进药物输送策略，改进复合电池材料，以及改进表面准备技术。