SGER: A Novel Biologically Inspired Painless Blood Collection Method

一种新的生物启发的无痛采血方法M。K. Ramasubramanian，PI，J. F. Tu，Co-PIMmechanical and Aerospace EngineeringNC州立大学，罗利，NC 27655rammk@ncsu.edu，jftu@untiy.ncsu.edu这项研究的主要目的是研究蚊子吸血的力学，完成这项任务所需的蚊子解剖学部分的材料和结构特征，并将理解转化为合成蚊子或由几个合成蚊子并行操作组成的蚊子群的工程规范，用于从活宿主（包括人类）无痛抽血。第二个目标是探索新的材料系统和制造工艺，用于大规模生产合成纤维束和长鼻。分析和实验方法将用于了解蚊子吸血的基本原理，纤维束的结构行为以及合成纤维束的制造。该研究提供了一个很好的机会，通过跨学科团队整合许多不同的科学领域，如生物材料，微尺度力学，MEMS，纳米制造和生物学。这项研究的成功将意味着定期和频繁地监测成人、儿童和婴儿的糖尿病等疾病的血液成分，对世界各地数百万人来说将是无痛的。将开发仿生设备设计和纳米制造的新课程，以教育未来的工程师。

A Novel Biologically Inspired Painless Blood Collection Method M. K. Ramasubramanian, PI, J. F. Tu, Co-PIMechanical and Aerospace EngineeringNC State University, Raleigh, NC 27655rammk@ncsu.edu, jftu@untiy.ncsu.edu The primary objective of this research is to study the mechanics of blood sucking by a mosquito, material and structural characterization of the parts of mosquito anatomy used needed in accomplishing the task, and translate the understanding into engineering specifications for a synthetic mosquito or a swarm of mosquitoes made up of several synthetic mosquitoes operating in parallel, for painless drawing of blood from a live host, including humans. The second objective is to explore novel material systems and manufacturing processes for the mass production of synthetic fascicle and proboscis. Both analytical and experimental approaches will be used to understand the fundamentals of blood sucking by a mosquito, structural behavior of the fascicle, and the manufacture of a synthetic fascicle. The research offers an excellent opportunity to integrate many different fields of science, such as biomaterials, micro-scale mechanics, MEMS, nano-manufacturing, and biology through an inter-disciplinary team. Success of this research will mean that the monitoring of blood constituents on a regular and frequent basis for diseases like diabetes in adults, children, and babies will be painless for millions of people around the world. New courses in bio-mimetic devices design, and nano-manufacturing will be developed for educating future engineers.