Integrating Fluorescence Spectroscopy Throughout the Undergraduate Chemistry and Biochemistry Curricula

将荧光光谱学融入整个本科化学和生物化学课程

• 批准号: 0411289
• 负责人: Steven Emory
• 金额: $ 3.54万
• 依托单位: Western Washington University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-15 至 2007-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0411289&HistoricalAwards=false
• 关键词: Integrating; Fluorescence; Spectroscopy; Throughout; Undergraduate

Chemistry (12) Spectroscopic methods, such as fluorescence, are used in diverse areas of chemical sciences to investigate chemical structure, molecular interactions, optical properties, biomolecular structure and function, kinetics, bioassays, and many other applications. By implementing the use of a fluorescence spectrophotometer, the integration of fluorescence spectroscopy throughout our undergraduate chemistry and biochemistry curricula is significantly enhancing the students' learning experience by 1) using modern instrumentation to develop practical skills in acquiring spectroscopic data and 2) using meaningful data to demonstrate the principles of spectroscopy and thereby helping students comprehend spectroscopic theory and the quantum mechanical basis of energy transitions. By exposing students to fluorescence and spectroscopic concepts throughout their college careers, students are expected to retain their knowledge of spectroscopic concepts, which will enable them to better apply this knowledge to scientific problems in the future. This project also is an essential component in Departmental efforts to modernize the undergraduate laboratories and implement project-based exercises. Fluorescence spectroscopy is being integrated into the following lower and upper division courses: general, analytical, instrumental, physical, and bio-chemistry. Our plans include the adaptation and implementation of fluorescence-based experiments from the primary research literature or from the Journal of Chemical Education, along with the development of new laboratory modules that emphasize basic spectroscopic theory and the complementary nature of many analytical techniques. The fluorometer also is being used in faculty-directed undergraduate research projects that students are encouraged to begin as early as their sophomore year. The fluorometer is centrally located in the Department's instrument laboratory and is made available to other departments via Western Washington University's (WWU's) Integrated Laboratory Network (ILN). The ILN is a computer network that enables remote access to instruments, software, on-line instrument tutorials, and data files. Intellectual Merit A fundamental understanding of spectroscopic methods and their applications is essential for physical scientists. This project addresses this need by implementing interdisciplinary and project-based laboratory exercises throughout the chemistry and biochemistry curricula. Broader Impacts The acquisition of the fluorometer significantly enhances the Department's and WWU's infrastructure for undergraduate research and education. The incorporation of fluorescence and molecular spectroscopy in the lower-division chemistry courses is impacting a diverse group of students, many of whom are not chemistry majors. The implementation of project-based, interdisciplinary experiments presents a more realistic picture of scientific discovery to students, and demonstrates the relevance and significance of scientific research. Experiments and methods developed as part of this project will be disseminated via the internet and in the chemical education literature.

光谱方法，如荧光，用于化学科学的不同领域，以研究化学结构，分子相互作用，光学性质，生物分子结构和功能，动力学，生物测定和许多其他应用。通过实施荧光分光光度计的使用，荧光光谱学在本科化学和生物化学课程中的整合，通过1）使用现代仪器来培养获取光谱数据的实践技能，2）使用有意义的数据来展示光谱学的原理，从而帮助学生理解光谱学理论和量子力学。能量转换的力学基础。通过让学生在整个大学生涯中接触荧光和光谱概念，学生有望保留光谱概念的知识，这将使他们能够更好地将这些知识应用于未来的科学问题。 该项目也是该部努力使本科生实验室现代化和实施基于项目的练习的重要组成部分。荧光光谱学被整合到以下低年级和高年级课程中：一般，分析，仪器，物理和生物化学。我们的计划包括从主要的研究文献或从化学教育杂志的荧光为基础的实验的适应和实施，沿着新的实验室模块，强调基本的光谱理论和许多分析技术的互补性的发展。荧光计也被用于教师指导的本科生研究项目，鼓励学生开始早在他们的大二。荧光计集中位于该部门的仪器实验室，并通过西华盛顿大学（WWU）的综合实验室网络（ILN）提供给其他部门。ILN是一个计算机网络，可以远程访问仪器、软件、在线仪器教程和数据文件。对光谱学方法及其应用的基本理解对物理科学家来说是必不可少的。本项目通过在整个化学和生物化学课程中实施跨学科和基于项目的实验室练习来满足这一需求。更广泛的影响荧光计的收购显着增强了部门和WWU的本科研究和教育的基础设施。在低年级化学课程中纳入荧光和分子光谱学正在影响不同的学生群体，其中许多人不是化学专业的学生。基于项目的跨学科实验的实施为学生提供了更真实的科学发现画面，并展示了科学研究的相关性和意义。作为该项目一部分开发的实验和方法将通过互联网和化学教育文献传播。