Mechanism of Particle Incorporation Into Microbial Cellulose

颗粒掺入微生物纤维素的机制

• 批准号: 0411693
• 负责人: B. Wayne Bequette
• 金额: --
• 依托单位: Rensselaer Polytechnic Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-15 至 2009-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0411693&HistoricalAwards=false
• 关键词: Mechanism; Particle; Incorporation; Into; Microbial

Mechanism of Particle Incorporation Into Microbial Cellulose Bequette BES-0411693In the proposed research, a rotating disk bioreactor will be used to produce cohesive cellulose films rapidly because of the high surface area, high volumetric efficiency, low power consumption, and easy control at the optimum sugar concentration and pH. The novel feature is that solids added to the medium enter the gel and are held at selected locations. Different solid materials such as silica gel, glass spheres, metallic powders, carbon, and common plant cellulose can be incorporated into the gel in which stripes or bands of solids can be formed. These new composites have potential applications for medicine, bioprocessing, and manufacture of novel forms of paper. There are a number of challenging fundamental problems in reactor design and control. Incorporation of solid particles into the gelatinous matrix of bacterial cellulose involves complicated fluid/particle hydrodynamics. The proposed research will measure rates of incorporation of solid particles as functions of angular velocity and concentration of particles in the medium by determining amounts in locations of the gel by examination with a microscope. Behavior of mixtures of different sizes and types of particles will be studied with consideration of hydrophobicity and zeta potential.

颗粒掺入微生物纤维素的机理Bequette BES-0411693在所提出的研究中，转盘生物反应器将用于快速生产内聚纤维素膜，因为其具有高表面积、高容积效率、低功耗以及易于控制最佳糖浓度和pH值。不同的固体材料，如硅胶、玻璃球、金属粉末、碳和常见的植物纤维素可以被掺入凝胶中，其中可以形成固体的条带或带。这些新的复合材料在医药、生物加工和新型纸的制造方面具有潜在的应用。在反应堆的设计和控制中有许多具有挑战性的基本问题。将固体颗粒掺入细菌纤维素的凝胶状基质中涉及复杂的流体/颗粒流体力学。拟议的研究将通过用显微镜检查确定凝胶位置的量来测量固体颗粒作为角速度和介质中颗粒浓度的函数的掺入率。不同尺寸和类型的颗粒的混合物的行为将与考虑的疏水性和zeta电位进行研究。