RUI: Oxidative Transformation Using User- and Eco-Friendly Hypervalent Iodine Reagents

RUI：使用用户友好且环保的高价碘试剂进行氧化转化

• 批准号: 0412614
• 负责人: T.K. Vinod
• 金额: $ 19.2万
• 依托单位: Western Illinois University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0412614&HistoricalAwards=false
• 关键词: RUI; Oxidative; Transformation; Using; User

The focus of this research is concerned with developing methods for the use of water-soluble hypervalent iodine reagents as oxidation agents. Hypervalent iodine (V) reagents, including chiral examples will be prepared and characterized. The reagents will then be used for the oxidation of alcohols and ethers and for the kinetic resolution of secondary alcohols.With this Research in Undergraduate Institutions ((RUI) award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. T.K. Vinod of the Department of Chemistry at Western Illinois University. Professor Vinod will focus his research efforts on developing new methodology for aqueous oxidations that involve the use of hypervalent iodine reagents. The methodology follows a green chemistry theme and will attempt to introduce eco-friendly approaches towards chemical reactions. In terms of broader impacts, the project will afford an excellent training ground for high school participants, undergraduates and masters level students.

这项研究的重点是开发使用水溶性高价碘试剂作为氧化剂的方法。高价碘(V)试剂，包括手性实例将被制备和表征。然后，这些试剂将用于醇和醚的氧化以及仲醇的动力学拆分。凭借这一本科院校研究奖(RUI)，有机和高分子化学计划支持西伊利诺伊大学化学系的T.K.Vinod博士的研究。维诺德教授将把他的研究重点放在开发涉及使用高价碘试剂的水氧化新方法上。该方法遵循绿色化学主题，并将试图引入对化学反应采取生态友好的方法。就更广泛的影响而言，该项目将为高中参与者、本科生和硕士水平的学生提供一个极好的培训场所。