SBIR Phase I: Rapid and Automated Differential Gene Expression Profiling

SBIR 第一阶段：快速、自动化差异基因表达谱分析

• 批准号: 0420114
• 负责人: Jian Tajbakhsh
• 金额: $ 9.99万
• 依托单位: MAXWELL SENSORS INC.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2005-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0420114&HistoricalAwards=false
• 关键词: SBIR; Phase; Rapid; Automated; Differential

This Small Business Innovation Research (SBIR) Phase I project proposes to develop a self-contained, automated microfluidic system for gene expression profiling. The proposed system is expected to significantly reduce the labor, equipment, and technical skills necessary to perform a DNA microarray experiment. The commercial application of this project will be to enable DNA microarray expression profiling for molecular characterization of diseases. Additional applications include comparative genomic hybridization, detection of single nucleotide polymorphisms and identification of thread agents like bacteria and viruses.

这个小企业创新研究（SBIR）第一阶段项目提出开发一个独立的，自动化的微流体系统，用于基因表达谱分析。所提出的系统预计将显着减少劳动力，设备和必要的技术技能进行DNA微阵列实验。该项目的商业应用将使DNA微阵列表达谱用于疾病的分子表征。 其他应用包括比较基因组杂交、单核苷酸多态性检测和细菌和病毒等线程代理的识别。