SBIR Phase I: Rapid and Automated Differential Gene Expression Profiling

这个小企业创新研究（SBIR）第一阶段项目建议开发一个独立的、自动化的微流体系统，用于基因表达谱分析。所提出的系统有望显著减少进行DNA微阵列实验所需的劳动力、设备和技术技能。该项目的商业应用将是使DNA微阵列表达谱能够用于疾病的分子表征。其他应用包括比较基因组杂交，检测单核苷酸多态性和鉴定线程剂如细菌和病毒。

This Small Business Innovation Research (SBIR) Phase I project proposes to develop a self-contained, automated microfluidic system for gene expression profiling. The proposed system is expected to significantly reduce the labor, equipment, and technical skills necessary to perform a DNA microarray experiment. The commercial application of this project will be to enable DNA microarray expression profiling for molecular characterization of diseases. Additional applications include comparative genomic hybridization, detection of single nucleotide polymorphisms and identification of thread agents like bacteria and viruses.