SBIR Phase II: Characterization of the Metabolic Competency of Centrifugal Bioreactors

SBIR 第二阶段：离心生物反应器代谢能力的表征

• 批准号: 0421962
• 负责人: Firoz Mistry
• 金额: --
• 依托单位: Kinetic Biosystems, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-10-01 至 2007-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0421962&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Characterization; Metabolic

This Small Business Innovation Research Phase II project is to develop a pilot-scale Centrifugal Bioreactor (CBR) for the continuous cultivation of hybridoma cells. The commercial application of this project will be in the biopharmaceutical industry for cell culture production of therapeutic agents. It is expected that the technology will reduce the scale and capital costs of commercial animal cell culture equipment and improve the quality and consistency of the secreted protein product.

这个小企业创新研究第二阶段项目是开发一个中试规模的离心生物反应器（CBR），用于杂交瘤细胞的连续培养。该项目的商业应用将在生物制药行业中用于治疗剂的细胞培养生产。预计该技术将降低商业动物细胞培养设备的规模和资本成本，并提高分泌蛋白产品的质量和一致性。