SGER: A New Approach to Assessing Microbial Risk in Drinking Water

SGER：评估饮用水微生物风险的新方法

• 批准号: 0439389
• 负责人: Kung-Hui Chu
• 金额: --
• 依托单位: University of Tennessee Knoxville
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-01-01 至 2005-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0439389&HistoricalAwards=false
• 关键词: SGER; New; Approach; Assessing; Microbial

0439389ChuThe proposed research develops and examines the efficiency of a novel molecular technique for identification and quantification of waterborne pathogens. A novel view of virulence genes as biomarkers for pathogenic species is proposed and could enable effective molecular quantification of pathogens in water samples. If successful, this study could develop an approach for applying molecular techniques as routine drinking water monitoring tools, and enabling the generation of quantitative data, that is necessary for assessing potential health threats. It is also expected that a new form of dose-response relationship, expressed as copies of virulence genes vs. health risk, will be developed.

本研究开发并检验了一种用于鉴定和定量水传播病原体的新型分子技术的效率。提出了一种新的毒力基因作为病原物种生物标志物的观点，可以有效地对水样中的病原体进行分子定量。如果成功，这项研究可以开发一种方法，将分子技术应用于常规饮用水监测工具，并能够生成定量数据，这是评估潜在健康威胁所必需的。预计还将发展出一种新的剂量-反应关系形式，即毒力基因拷贝数与健康风险之间的关系。