SBIR Phase II: An Automated Water Pathogen Monitoring System

这项小型企业创新研究（SBIR）二期项目旨在开发一种自动化仪器，利用免疫测定和电化学相结合的方法，快速和特异性地检测市政供水中的水生病原体。虽然该仪器的一次性药筒可以指定用于几乎任何感兴趣的病原体，但该项目将主要集中在微小隐孢子虫卵囊的检测上。细小梭状芽孢杆菌是对国家供水的威胁，对常见的抗生素没有反应，并且抵抗水净化处理。该项目的商业应用将是监测饮用水供应中的病原体。这将包括在水源、分配网络以及装瓶和包装设施对水进行测试。拟议的装置最终将适用于紧急现场使用、有安全意识的消费者家庭使用以及医疗、工业、娱乐和战斗用途。

This Small Business Innovation Research (SBIR) Phase II project aims to develop an automated instrument for rapid and specific detection of waterborne pathogens in municipal water supplies using methods combining immunoassay with electrochemistry. Although the disposable cartridges for this instrument could be specified for nearly any pathogen of interest, this project will focus primarily on the detection of Cryptosporidium parvum oocysts. C. parvum is a threat to the nation's water supply, does not respond to common antibiotics and resists water purification treatments. The commercial application of this project will be on the monitoring of drinking water supplies for pathogens. This would include testing of water at the source, in distribution networks, and at bottling and packaging facilities. The proposed device would eventually be adapted for emergency field use, for home use by safety conscious consumers, and for medical, industrial, recreational and combat purposes.