Filament Dynamics in Three-Dimensional Reaction-Diffusion Systems

三维反应扩散系统中的细丝动力学

• 批准号: 0513912
• 负责人: Oliver Steinbock
• 金额: $ 44.75万
• 依托单位: Florida State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0513912&HistoricalAwards=false
• 关键词: Filament; Dynamics; Three; Dimensional; Reaction

Oliver Steinbock of Florida State University is suuported by a grant from the Theoretical and Computational Chemistry program wihin the Division of Chemistry for research on filament dynamics in three dimensional reaction-diffusion systems. A systematic study of three dimensional chemical waves in a variant of the Belousov-Zhabotinsky (BZ) reaction is being carried out to test theoretical predictions of interesting scroll waves rotating around circular filaments and other complex wave dynamics. These new experiments are significantly expanding the number of experimental studies of this important reaction thought to be a model for excitable media in biological systems, such as cardiac and neural tissue. Steinbock's research group is devising new experiemental strategies that will allow the controlled fabrication of heterogeneous three dimensional systems that may mimic the heterogeneities found in biological tissue. Cardiac tissue, in particular, is suggested to have the same type of dynamical properties as the BZ medium, so broader impacts are expected in the understanding of sudden cardiac death, shown in prior theoretical studies to be related to the filament dynamics to be studied here.

佛罗里达州立大学的奥利弗Steinbock获得了化学系理论与计算化学项目的资助，用于研究三维反应扩散系统中的细丝动力学。正在进行一项系统的研究，三维化学波的一个变种的Belousov-Zhabotinsky（BZ）反应，以测试理论预测的有趣的螺旋波旋转周围的圆形细丝和其他复杂的波动动力学。这些新的实验显著扩大了这一重要反应的实验研究数量，该反应被认为是生物系统（如心脏和神经组织）中可兴奋介质的模型。斯坦博克的研究小组正在设计新的实验策略，这将允许控制制造异质三维系统，这些系统可以模仿生物组织中发现的异质性。心脏组织，特别是，建议具有相同类型的动态特性的BZ介质，因此更广泛的影响，预计在理解心脏性猝死，在先前的理论研究中所示的灯丝动力学在这里进行研究。