Selective Activation of Carbon-Fluorine Bonds Using Transition Metal Complexes

使用过渡金属配合物选择性活化碳氟键

• 批准号: 0518170
• 负责人: Russell Hughes
• 金额: $ 37.5万
• 依托单位: Dartmouth College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0518170&HistoricalAwards=false
• 关键词: Selective; Activation; Carbon; Fluorine; Bonds

Professor Russell Hughes, a faculty member in the Department of Chemistry at Dartmouth College, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program to develop methods for activating normally inert carbon-fluorine bonds with transition metal reagents. The conversion of C-F bonds to either C-H or C-C bonds is one goal of this project. The impact of volatile fluorocarbon derivatives on atmospheric chemistry is substantial, and the ability to break strong C-F single bonds is an important component of this research project. Replacement of chlorofluorocarbon chemicals as refrigerants and cleaning solvents is an important goal for the twenty-first century. Hydrofluorocarbons are an attractive alternative with favorable properties relative to the chlorinated analogs, and development of chemical transformations of carbon fluorine bonds is necessary to capitalize on the potential use of these chemicals. Training students in areas of chemistry relevant to global warming provides a work force that is better prepared for future planning with respect to environmental impact considerations.

达特茅斯学院化学系的教师Russell Hughes教授得到了无机，生物无机和有机化学计划的支持，以开发用过渡金属试剂激活通常惰性的碳-氟键的方法。 将C-F键转化为C-H键或C-C键是该项目的目标之一。挥发性碳氟化合物衍生物对大气化学的影响是巨大的，而破坏强C-F单键的能力是本研究项目的重要组成部分。替代氯氟烃化学品作为制冷剂和清洁溶剂是世纪的一个重要目标。 氢氟烃是一种有吸引力的替代品，相对于氯化类似物具有有利的性质，并且开发碳氟键的化学转化对于利用这些化学品的潜在用途是必要的。 在与全球变暖有关的化学领域对学生进行培训，为今后在环境影响方面的规划提供了更好的准备。