CAREER: Nucleic Acid Engineering -- Integrating DNA into Biomaterial Research and Education

职业：核酸工程——将 DNA 融入生物材料研究和教育

• 批准号: 0547330
• 负责人: Dan Luo
• 金额: --
• 依托单位: Cornell Univ - State: AWDS MADE PRIOR MAY 2010
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-15 至 2011-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0547330&HistoricalAwards=false
• 关键词: CAREER; Nucleic; Acid; Engineering; Integrating

0547330LuoThe overall goals of this research focus on Nucleic Acid Engineering -- integratingDNA into biomaterial research, not by just mimicking biomolecules, but by actually usingbiomolecules themselves, DNA in this case, to construct new materials and nanodevices.Departing from the conventional concept of DNA being just a genetic material, it is proposed here to deliberately ignore DNA's various genetic roles and instead to use DNA as a generic building block for the construction of novel DNA-based biomaterials whose architectures can be controlled at the nanoscale, and whose properties can be further tailored towards specific biomedical and biotechnological applications.

0547330罗本研究的总体目标集中在核酸工程--将DNA整合到生物材料研究中，不仅仅是通过模仿生物分子，而是实际使用生物分子本身，在这种情况下是DNA，来构建新材料和纳米器件。这里建议故意忽略DNA的各种遗传作用，而是使用DNA作为构建新的基于DNA的生物材料的通用构建块，所述生物材料的结构可以在纳米级控制，并且其性质可以进一步针对特定的生物医学和生物技术应用而定制。