SGER: Ecotoxicological and functional genomic responses of Killifish in the aftermath of Hurricane Katrina

SGER：卡特里娜飓风过后鳉鱼的生态毒理学和功能基因组反应

• 批准号: 0553523
• 负责人: Andrew Whitehead
• 金额: $ 2.99万
• 依托单位: Louisiana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-10-15 至 2006-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0553523&HistoricalAwards=false
• 关键词: SGER; Ecotoxicological; functional; genomic; responses

0553523 Whitehead The overarching goal of this proposed research is to evaluate the effects of Hurricane Katrina fallout on the health of marsh fishes, and to test whether environmental chemical concentrations are predictive of functional genomic responses and whether functional genomic responses are predictive of physiological responses. This will be achieved by coupling functional genomic tools with physiological measures of stress and toxicity, and by integrating observations collected in the field with controlled laboratory experiments. Biological data will eventually be coupled with analytical chemistry to test whether concentrations of chemicals associated with the aftermath of Hurricane Katrina are predictive of biological responses, and to examine the timecourse of recovery in the Lake Ponchatrain ecosystem

这项拟议研究的总体目标是评估卡特里娜飓风对沼泽鱼类健康的影响，并测试环境化学浓度是否可以预测功能性基因组反应，以及功能性基因组反应是否可以预测生理反应。这将通过将功能基因组工具与应激和毒性的生理测量相结合，以及将现场收集的观察结果与对照实验室实验相结合来实现。生物数据最终将与分析化学相结合，以测试与卡特里娜飓风后果有关的化学物质浓度是否可以预测生物反应，并检查庞查特雷恩湖生态系统恢复的时间进程