U.S.-Poland Summer Program on the Structural Role of Metal Ions in Modified RNA Enzymes

OISE 05- 53951 Stefan Franzen北卡罗莱纳州立大学This美国-波兰项目是一个夏季本科生项目，总部设在亚当密茨凯维奇大学（AMU）和波兰国家科学院（PAN）在波兹南，波兰。 主要研究人员是北卡罗来纳州州立大学的Stefan Franzen博士和Adam Mickiewicz大学的Stefan Jurga。该计划的概念是为一个研究项目开发一个教育组件，该项目涉及对RNA结构和功能的普遍感兴趣的新问题的合作研究。该研究的主题是研究金属离子对用作RNA酶的修饰核苷酸和寡核苷酸的影响。PI和co-PI最近开始了一项研究计划，该计划涉及开发能够合成新型纳米材料的新型催化RNA。研究目标包括确定能够进行催化过程的RNA分子的结构和功能。 该计划的理念是，本科夏季研究将受益于具有共同特征的协同项目。 通过这种方式，夏季研究将为学生提供连贯的培训。 学生们将有助于更大的努力，因此他们将从彼此的实验以及从与AMU和PAN教授以及首席研究员的互动中学习。

OISE 05-53951Stefan FranzenNorth Carolina State UniversityThis U.S.-Polish project is a summer undergraduate student program based at Adam Mickiewicz University (AMU) and the Polish National Academy of Sciences (PAN) in Poznan, Poland. The principal investigators are Dr. Stefan Franzen at North Carolina State University and Stefan Jurga from Adam Mickiewicz University. The concept for the program is to develop an educational component to a research project that involves collaborative research on a novel problem of general interest for RNA structure and function. The theme of the research is the study of the effects of metal ions on modified nucleotides and oligonucleotides that are used as RNA enzymes. The PI and co-PIs have recently embarked on program of research that involves the development novel catalytic RNAs that are capable of synthesizing novel nanoscale materials. The research goals involve determining the structure and function of the RNA molecules that are capable of carrying out catalytic processes. The philosophy of the program is that undergraduate summer research will benefit from synergistic projects that have common features. In this way the summer research will provide a coherent training for students. The students will contribute to a larger effort and hence they will be learning from each others experiments as well as from the interaction with professors at both AMU and PAN as well as with the principal investigator.