权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

DISSERTATION RESEARCH: The Effects of Sex-Differential Parasitism on Disease Dynamicsin a Plant-Fungal System

论文研究：性别差异寄生对植物真菌系统疾病动态的影响

基本信息

批准号：
0608447
负责人：
Janis Antonovics
金额：
$ 1.1万
依托单位：
University of Virginia Main Campus
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2006
资助国家：
美国
起止时间：
2006-08-15 至 2008-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=0608447&HistoricalAwards=false
关键词：
DISSERTATION RESEARCH Effects Sex Differential

项目摘要

Sex differences in infection rates are widespread in natural populations of organisms ranging from plants and invertebrates to amphibians, birds, and mammals. Sex differences are also characteristic of many human diseases, such as HIV. This study will develop a mathematical model to investigate the effects of sex-specific differences in transmission on disease dynamics. Experimental populations of Silene latifolia infected with the pollinator-transmitted fungal pathogen Microbotryum violaceum will be established to estimate the within- and between-sex disease transmission, as well as sex-specific differences in recovery, disease-induced sterility, and mortality. To complement the experimental work, natural populations will be marked to estimate transmission, recovery, and survival rates. Studying disease dynamics in two-sex systems is fundamental for guiding disease control strategies in species of agricultural, medical, and conservation concern. This work will contribute to understanding the spread and maintenance of disease in natural populations. This issue is important because disease drives ecological abundance, and natural populations may act as reservoirs for diseases that are important in agriculture and for human health. These serious concerns make understanding disease dynamics in natural systems imperative.

在从植物和无脊椎动物到两栖动物、鸟类和哺乳动物等各种生物的自然种群中，感染率的性别差异普遍存在。性别差异也是许多人类疾病的特征，例如艾滋病毒。这项研究将开发一个数学模型，以调查不同性别传播差异对疾病动力学的影响。将建立感染传粉者传播的真菌病原体紫罗兰的实验种群，以估计疾病在性别内和性别之间的传播，以及不同性别在恢复、疾病导致的不育症和死亡率方面的差异。为了补充实验工作，将对自然种群进行标记，以估计传播、恢复和存活率。研究两性系统中的疾病动态对于指导农业、医学和保护物种的疾病控制策略是基本的。这项工作将有助于了解疾病在自然人群中的传播和维持。这个问题很重要，因为疾病推动了生态的丰富，而自然人口可能成为疾病的宿主，这些疾病对农业和人类健康都很重要。这些严重的担忧使得理解自然系统中的疾病动态变得迫切。