Thermodynamic and Kinetic Studies of Binding, Radical, and Radical Promoted Reactions of Sulfur Ligands at Transition Metal Centers.

过渡金属中心硫配体的结合、自由基和自由基促进反应的热力学和动力学研究。

• 批准号: 0615743
• 负责人: Carl Hoff
• 金额: $ 43.6万
• 依托单位: University of Miami
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-15 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0615743&HistoricalAwards=false
• 关键词: Thermodynamic; Kinetic; Studies; Binding; Radical

This award in the Inorganic, Bioinorganic and Organometallic Chemistry supports research by Professor Carl Hoff at the University of Miami to gain a fundamental understanding of the rules of how catalysts facilitate the Haber process by unraveling the energy content of key intermediates along the reaction pathway. vFocus is on the first logical intermediate N2H, which is highly unstable unless it is bound to a metal complex or other catalytic species. The two principle questions to be addressed are how this first step can be made more favorable in terms of the energy changes involved. The second is how it can be made to occur faster by addition of a third party (a mimic of an enzyme cofactor) to speed up the reaction process. Development of a low temperature catalyst for nitrogen fixation would have a tremendous impact and result in energy savings in the production of nitrogen compounds. Infrastructure and collaborative linkage will be established between the Miami program and that of Professor Josh Telser (Roosevelt Univesity) and Professor Alex Angerhofer (University of Florida and National High Magnetic Field Laboratory). Undergraduate students from any of these institutions will be supported for research work at any of the others. Significant populations of traditionally under represented groups are present at all three campuses, particularly Hispanic students at Miami, and African American students at Roosevelt. The techniques and methods learned will provide a rich and diverse student education with the training essential for progress in a competitive chemical endeavors.

这一无机化学、生物无机化学和金属有机化学奖支持了迈阿密大学的卡尔·霍夫教授的研究，他的研究旨在从根本上了解催化剂如何通过分解反应路径上关键中间体的能量含量来促进哈伯过程。VFocus位于第一个逻辑中间体N2H上，N2H是高度不稳定的，除非它与金属络合物或其他催化物种结合。需要解决的两个主要问题是，如何才能使这第一步在所涉及的能源变化方面更有利。第二个问题是如何通过添加第三方(一种酶辅助因子的模拟物)来加速反应过程，从而使其发生得更快。开发一种用于固氮的低温催化剂将对氮化合物的生产产生巨大的影响并节省能源。迈阿密计划将与罗斯福大学的Josh Telser教授和佛罗里达大学和国家高磁场实验室的Alex Angerhofer教授的计划建立基础设施和协作联系。这些机构中的任何一个的本科生在其他任何一个机构的研究工作都将得到支持。在所有三个校区，都有大量传统上代表不足的群体，特别是迈阿密的西语裔学生和罗斯福的非裔美国学生。所学的技术和方法将为学生提供丰富和多样化的教育，并提供在竞争激烈的化学努力中取得进展所必需的培训。