Cometabolic Degradation of Estrogen Compounds in Activated Sludge Treatment Processes

活性污泥处理过程中雌激素化合物的共代谢降解

• 批准号: 0652109
• 负责人: H.David Stensel
• 金额: $ 30万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0652109&HistoricalAwards=false
• 关键词: Cometabolic; Degradation; Estrogen; Compounds; Activated

CBET-0652109H. David StenselUniversity of WashingtonCometabolic Degradation of Estrogen Compounds in Activated Sludge Treatment ProcessesEstrogens constitute a group of important contaminants that may contribute to low fish populations in freshwaters receiving discharges from municipal wastewater treatment facilities. Information on their biodegradation is needed to design effective treatment methods. This research project will conduct laboratory studies to understand the biodegradation mechanism for estrogen and the factors that affect estrogen biodegradation rates in nitrifying wastewater systems and advance methods to enhance estrogen degradation. Initial studies will involve fundamental investigations of EE2 degradation of the synthetic birth control pharmaceutical, 17a-ethynyl estradiol (EE2), by pure cultures of ammonium-oxidizing bacteria (AOB), N. europaea, Nitrosospira, and Nitrosomonas oligotropha. Studies of EE2degradation mechanisms will increase understanding of the role of various enzymatic reactions and assess degradation products. Biodegradation rate data will be obtained for the estrogen compounds for a process model that includes the effects of estrogen, ammonium and dissolved oxygen concentration, and effects of mixtures of estrogens in the ng/L to ug/L range. The estrogen degradation/nitrification model will be used to design optimized activated sludge processes. The estrogen degradation ability of other cometabolic organisms, such as methane- and phenol-oxidizing bacteria also will be investigated.

生态旅游- 0652109 h。华盛顿大学活性污泥处理过程中雌激素化合物的代谢降解雌激素构成了一组重要的污染物，可能导致城市污水处理设施排放的淡水中鱼类数量减少。需要有关其生物降解的信息来设计有效的处理方法。本课题将开展实验室研究，了解雌激素在硝化废水系统中的生物降解机制和影响雌激素生物降解率的因素，并提出增强雌激素降解的方法。最初的研究将包括通过纯培养氨氧化细菌（AOB）、N. europaea、亚硝基螺旋菌和少tropha亚硝基单胞菌，对合成节育药物17a-乙基雌二醇（EE2）的EE2降解进行基础研究。对ee2降解机制的研究将增加对各种酶促反应作用的理解，并评估降解产物。将获得雌激素化合物的生物降解率数据，该过程模型包括雌激素，铵和溶解氧浓度的影响，以及雌激素在ng/L至ug/L范围内的混合物的影响。雌激素降解/硝化模型将用于设计优化的活性污泥工艺。其他代谢生物，如甲烷和酚氧化细菌的雌激素降解能力也将被研究。