NIRT: Active nanofluidic manufacturing and hierarchical assembly of anisotropic nanocolloids

NIRT：各向异性纳米胶体的活性纳米流体制造和分层组装

• 批准号: 0707383
• 负责人: Michael Solomon
• 金额: $ 110万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0707383&HistoricalAwards=false
• 关键词: NIRT; Active; nanofluidic; manufacturing; hierarchical

A rapidly expanding research frontier is the fluidic manufacture of anisotropic particle building blocks. Simultaneously, the concept of encoding information into the sequence, shape and symmetry of anisotropic particle building blocks so they can assemble into complex three-dimensional (3D) structures offers tremendous potential. Taken together, these two areas each represent one level of a new hierarchical assembly paradigm that can input spherical nanocolloidal precursors and, by way of anisotropic building blocks, output complex 3D terminal structures with a range of new, active functionalities. Yet, to date, the two levels of the assembly hierarchy have advanced independently on the different scales of microparticles (fabrication) and molecules (anisotropic assembly) rather than together at the nanoscale. In this project we seek to address the key fundamental scientific challenges needed to realize this hierarchical paradigm at nanoscale dimensions where there is rich new potential for applications requiring active functionality for materials in photonics, electronics and energy management. In this aim we are supported by our recent discovery that fluidic processing can be used to assemble microparticles into permanently bonded anisotropic building blocks with high sequence and shape fidelity. Our prior research has additionally shown vis simulation that anisotropic building blocks are a key foundation from which 3D terminal structures can be assembled.Building on this experience in fluidic manufacturing and anisotropic particle assembly, our work plan is organized to address four key fundamental science and engineering design questions that arise as the hierarchical assembly paradigm is extended to the nanoscale. First, to address the potential for fouling in nanofluidic channels, as particle size is reduced into the nanoscale range, we will study how anisotropic building blocks interact with fluidic channels of complex design. Second, we will harness this understanding to discover the fluidic designs that optimally produce building blocks of novel sequence, shape and chirality. Third, given that a suite of such novel building blocks are now available, and that a given complex 3D terminal structure has been targeted for assembly, we will search for optimal ways to design the anisotropic building blocks for self- and guided assembly. Finally, we will discover how to execute self- or guided- assembly operations so as to achieve the target structures from the manufactured building blocks. These objectives, each with intrinsic intellectual merit, will be addressed through an integrated research program that brings to bear our state-of-the-art capabilities in nanofabrication, fluidic manufacturing, nanocolloid assembly, direct visualization by confocal and electron microscopy and computer simulation of anisotropic building block interactions and assembly. Simultaneously, by developing new data repository and wiki cyber tools within the National Science Digital Library framework, we will create a clear conduit for dissemination of our discoveries so as to contribute to the integration of the broader national nanoscale science and engineering community, to the training and education of our students and to the improvement of the participation of underrepresented groups and low to moderate income students from the southeastern Michigan area. The broader impact of our work will be to advance the national effort in nanoscale science and engineering by creating underlying scientific understanding that enables the penetration of fluidic manufacturing and anisotropic building block assembly into the nanocolloidal size regime where potential applications are richest. Furthermore, by creating new avenues for research dissemination and learning through the framework of data repositories and wikis, we can further integrate the national research communities, our students and our region into the exciting research frontier of nanofluidic manufacturing and anisotropic building block assembly.

快速扩展的研究边界是各向异性粒子构建块的流体生产。 同时，将信息编码为各向异性粒子构建块的序列，形状和对称性的概念，因此它们可以组装成复杂的三维（3D）结构具有巨大的潜力。 综上所述，这两个区域代表了一个新的层次组件范式的一个级别，该范围可以输入球形纳米胶体前体，并通过各向异性构建块，输出具有一系列新型活性功能的复杂3D终端结构。 然而，迄今为止，组装层次结构的两个级别已在微粒（制造）和分子（各向异性组装）的不同尺度上独立发展，而不是在纳米级。 在这个项目中，我们试图解决在纳米级维度上实现这种层次范式所需的关键基本科学挑战，在这些层次上，在需要使用光子学，电子和能源管理的材料功能的应用程序中，有巨大的应用潜力。 在这个目的中，我们最近发现的是，流体加工可用于将微粒组装成具有高序列和形状保真度的永久粘合各向异性构建块。 我们先前的研究还表明，有关各向异性的构建块是可以组装3D终端结构的关键基础。建立在流动制造和各向异性粒子组装方面的经验，我们的工作计划是为了解决四个关键的科学和工程设计问题，这些问题是在层次组件中出现的四个关键的基本科学和工程设计问题。 首先，为了解决纳米流体通道中污染的潜力，随着粒径减小到纳米级范围，我们将研究各向异性构建块如何与复杂设计的流体通道相互作用。 其次，我们将利用这种理解来发现最佳产生新型序列，形状和手性的基础的流体设计。 第三，鉴于现在有一套新颖的构建块，并且给定的复杂的3D终端结构已成为组装，我们将搜索设计各向异性构建块的最佳方法，以进行自我和引导组装。 最后，我们将发现如何执行自我或有指导的组装操作，以从制造的构件中实现目标结构。 这些目标都将通过一项综合研究计划来解决，该计划将带来我们在纳米造型，流体制造，纳米胶体组件，共焦和电子显微镜和计算机模拟的型号构造块相互作用和组件的直接可视化方面的最先进功能。 同时，通过在国家科学数字图书馆框架内开发新的数据存储库和Wiki网络工具，我们将建立一个清晰的渠道，以传播我们的发现，从而为更广泛的国家纳米级科学和工程社区的融合做出贡献，以对学生的培训和教育，对学生的培训和教育，以改善群体和低位学生的参与率不足的学生和低至中等的学生的参与。 我们工作的更广泛的影响是通过创造潜在的科学理解来促进纳米级科学和工程的全国努力，从而使流体制造和各向异性构建块组件渗透到潜在的应用最丰富的情况下进入纳米机固定尺寸。 此外，通过通过数据存储库和Wiki的框架创建新的研究传播和学习途径，我们可以进一步将国家研究社区，我们的学生和我们的地区进一步整合到纳米流利制造和各向异性构件组件的令人兴奋的研究边界。