Collaborative Research: EMT - Programmable Molecular Movements

DNA纳米技术是科学的一个分支，它使科学家能够利用设计好的DNA分子的信息内容构建纳米机械装置和规则阵列；这类物种的组成部分通常是由设计成分支的分子组成的DNA“瓦片”。这些结构的有效性和多样性可以通过让瓷砖根据逻辑操作进行自组装而不是通过单一的设计来显著增强。这项研究涉及到编程一系列的瓷砖来组织一组DNA纳米机械设备根据给定的输入。该装置由两种不同相关类型的分子组成，因此，当一种分子向一个方向旋转机械臂时，另一种分子向相反方向旋转，从而导致分子编排。这种编排将用于修改经过机械臂的行走设备所携带的负载的内容。该系统的重要性在于，它将为可编程的分子级装配线提供原型，能够通过算法组织和重新定位潜在的纳米电子元件，使其进入所需的排列方式，从而产生有用的电路。本研究涉及到使用与Wang瓷砖对应的TX DNA瓷砖来模拟具有输出的有限状态机，以设计排列的初始基行。根据基行编码，将特定的TX块和包含机器人手臂和PX-JX2设备的2状态设备盒组织成2D阵列。配备货物的行走器将在已经组织好的平台上移动。然后，根据创建数组的计算结果修改货物。

DNA Nanotechnology is a branch of science that enables scientists to build nanomechanical devices and regular arrays, using the information content of designed DNA molecules; the components of such species are usually DNA 'tiles' made from molecules designed to branch. The effectiveness and diversity of these constructs can be enhanced markedly by getting the tiles to self-assemble according to logical operations, rather than by a single design. This research involves programming a series of tiles to organize a group of DNA nanomechanical devices according to a given input. The devices consist of two different related types of molecules, so that when one rotates a robot arm in one direction, the other rotates it in the opposite direction, thereby leading to molecular choreography. This choreography will be used to modify the contents of a load carried by a walking device past the robot arms. The importance of this system is that it will prototype programmable molecular-scale assembly lines, capable of algorithmically organizing and relocating potential nanoelectronic components into desired arrangements that will result in useful circuitry.This research involves using TX DNA tiles that correspond to Wang tiles to simulate a finite state machine with output, to design the initial base row for the arrangement. According to the coding of the base row, specific TX tiles and 2-state-device-containing cassettes containing robot arms and PX-JX2 devices are then organized into a 2D array. A walker equipped with cargo will move across the platform that has been organized. The cargo is then modified as a consequence of the computation that creates the array.