Collaborative Research: EMT - Programmable Molecular Movements

DNA纳米技术是一门科学的分支，它使科学家能够利用设计的DNA分子的信息内容来构建纳米机械设备和规则阵列；这类物种的成分通常是由设计为分支的分子制成的DNA“瓷砖”。这些结构的有效性和多样性可以通过让瓷砖根据逻辑操作自组装来显著增强，而不是通过单一的设计。这项研究涉及根据给定的输入对一系列瓷砖进行编程，以组织一组DNA纳米机械设备。这些设备由两种不同类型的相关分子组成，因此当一个分子向一个方向旋转机械臂时，另一个分子会使机械臂朝着相反的方向旋转，从而导致分子编排。这种编排将用于修改行走设备通过机器人手臂所承载的负荷的内容。这个系统的重要性在于它将成为可编程分子规模装配线的原型，能够以算法将潜在的纳米电子元件组织和重新定位到期望的排列中，从而产生有用的电路。这项研究涉及使用与Wang片对应的TX DNA片来模拟具有输出的有限状态机，以设计排列的初始基准行。根据基本行的编码，然后将特定的TX瓦片和包含机器人手臂和PX-JX2设备的2状态设备盒式磁带组织成2D阵列。一个携带货物的步行者将在已经组织好的平台上移动。然后，作为创建数组的计算的结果，修改货物。

DNA Nanotechnology is a branch of science that enables scientists to build nanomechanical devices and regular arrays, using the information content of designed DNA molecules; the components of such species are usually DNA 'tiles' made from molecules designed to branch. The effectiveness and diversity of these constructs can be enhanced markedly by getting the tiles to self-assemble according to logical operations, rather than by a single design. This research involves programming a series of tiles to organize a group of DNA nanomechanical devices according to a given input. The devices consist of two different related types of molecules, so that when one rotates a robot arm in one direction, the other rotates it in the opposite direction, thereby leading to molecular choreography. This choreography will be used to modify the contents of a load carried by a walking device past the robot arms. The importance of this system is that it will prototype programmable molecular-scale assembly lines, capable of algorithmically organizing and relocating potential nanoelectronic components into desired arrangements that will result in useful circuitry.This research involves using TX DNA tiles that correspond to Wang tiles to simulate a finite state machine with output, to design the initial base row for the arrangement. According to the coding of the base row, specific TX tiles and 2-state-device-containing cassettes containing robot arms and PX-JX2 devices are then organized into a 2D array. A walker equipped with cargo will move across the platform that has been organized. The cargo is then modified as a consequence of the computation that creates the array.