Collaborative Research: EMT - Programmable Molecular Movements
Collaborative Research: EMT - Programmable Molecular Movements
批准号:
0726378
负责人:
Nadrian Seeman
金额:
$22.5万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-09-15 至 2011-08-31
中文摘要
DNA纳米技术是科学的一个分支,它使科学家能够利用设计的DNA分子的信息内容来构建纳米机械装置和规则阵列;这些物种的组成部分通常是由设计成分支的分子制成的DNA“瓦片”。 这些结构的有效性和多样性可以通过让瓦片根据逻辑运算而不是通过单一设计进行自组装来显著增强。 这项研究涉及对一系列瓦片进行编程,以根据给定的输入来组织一组DNA纳米机械设备。 这些装置由两种不同的相关类型的分子组成,因此当一个方向旋转机器人手臂时,另一个方向旋转它,从而导致分子编排。 这种编排将用于修改由步行设备携带的负载的内容,通过机器人手臂。 这个系统的重要性在于它将成为可编程分子级装配线的原型,能够通过算法将潜在的纳米电子元件组织和重新定位到所需的排列中,从而产生有用的circuits.This研究涉及使用TX DNA瓦片,对应于Wang瓦片来模拟具有输出的有限状态机,以设计排列的初始基行。 根据基行的编码,特定的TX瓦片和包含机器人臂和PX-JX 2器件的包含2状态器件的盒然后被组织成2D阵列。 一个装有货物的步行者将穿过已经组织好的平台。 然后,货物作为创建数组的计算的结果被修改。
英文摘要
DNA Nanotechnology is a branch of science that enables scientists to build nanomechanical devices and regular arrays, using the information content of designed DNA molecules; the components of such species are usually DNA 'tiles' made from molecules designed to branch. The effectiveness and diversity of these constructs can be enhanced markedly by getting the tiles to self-assemble according to logical operations, rather than by a single design. This research involves programming a series of tiles to organize a group of DNA nanomechanical devices according to a given input. The devices consist of two different related types of molecules, so that when one rotates a robot arm in one direction, the other rotates it in the opposite direction, thereby leading to molecular choreography. This choreography will be used to modify the contents of a load carried by a walking device past the robot arms. The importance of this system is that it will prototype programmable molecular-scale assembly lines, capable of algorithmically organizing and relocating potential nanoelectronic components into desired arrangements that will result in useful circuitry.This research involves using TX DNA tiles that correspond to Wang tiles to simulate a finite state machine with output, to design the initial base row for the arrangement. According to the coding of the base row, specific TX tiles and 2-state-device-containing cassettes containing robot arms and PX-JX2 devices are then organized into a 2D array. A walker equipped with cargo will move across the platform that has been organized. The cargo is then modified as a consequence of the computation that creates the array.
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Multidimensional Materials Assembled by DNA Based Information
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批准号:1708776
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项目类别:Standard Grant
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资助金额:$46.5万
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财政年份:2017
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负责人:Nadrian Seeman
-
依托单位:
Small: Collaborative Research: Programmed Cyclic Molecular Dancing on 2D Origami Lattices
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批准号:1526650
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项目类别:Standard Grant
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资助金额:$25.0万
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财政年份:2015
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负责人:Nadrian Seeman
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依托单位:
AF: Small: Collaborative Research: Active DNA Assembly of Aperiodic Structures
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批准号:1117210
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项目类别:Standard Grant
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资助金额:$29.58万
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财政年份:2011
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负责人:Nadrian Seeman
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依托单位:
NIRT: Active Nanostructures for Nucleic Directed synthesis of Organic Functional Polymers
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批准号:0608889
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项目类别:Standard Grant
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资助金额:$150.0万
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财政年份:2006
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负责人:Nadrian Seeman
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依托单位:
NANO: EMT: Revolutionary 3D Nanoarchitectures to Organize the Assembly of Computing Elements
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批准号:0523290
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项目类别:Standard Grant
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资助金额:$30.0万
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财政年份:2005
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负责人:Nadrian Seeman
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依托单位:
SGER: Feasibility Study of DNA-Directed Polymer Synthesis
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批准号:0548774
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项目类别:Standard Grant
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资助金额:$20.0万
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财政年份:2005
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负责人:Nadrian Seeman
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依托单位:
Nano: Programmable Finite State Machines Achieved by DNA Self-Assembly
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批准号:0432009
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项目类别:Continuing Grant
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资助金额:$30.0万
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财政年份:2004
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负责人:Nadrian Seeman
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依托单位:
Acquisition of an Atomic Force Microscope for DNA Nanotechnology Research and Education
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批准号:0113879
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项目类别:Standard Grant
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资助金额:$9.0万
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财政年份:2001
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负责人:Nadrian Seeman
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依托单位:
NIRT/GOALI: DNA-Based Nanomechanical Devices
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批准号:0103002
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项目类别:Standard Grant
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资助金额:$150.0万
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财政年份:2001
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负责人:Nadrian Seeman
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依托单位:
国内基金
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