Collaborative Research: Assembling the Euteleost Tree of Life - Addressing the Major Unresolved Problem in Vertebrate Phylogeny

合作研究：组装Euteleost生命树——解决脊椎动物系统发育中未解决的主要问题

• 批准号: 0732969
• 负责人: Guoqing Lu
• 金额: $ 19.39万
• 依托单位: University of Nebraska at Omaha
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-10-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0732969&HistoricalAwards=false
• 关键词: Collaborative; Research; Assembling; Euteleost; Tree

This project will involve investigators from eight institutions working to resolve evolutionary relationships within the euteleost fishes, which represent over one third of vertebrate diversity. An important component will be education of the public on the importance, evolutionary history, and diversity of these animals. Phylogenetic analyses will employ DNA sequence data from 20 genes in 1,500 species representing all euteleost families, and approximately 450 morphological characters from 300 euteleost lineages. Resulting phylogenetic hypotheses will be used to facilitate understanding of the evolution of fish diversity and re-assess and revise the systematics of euteleosts. Research on the euteleost tree of life will be integrated into science education by using euteleost phylogeny as a framework for exploring the evolution of morphological, genetic, developmental, and behavioral diversity of fishes. This will be developed as an instructional guide, a "Fish ToL Activity Book," directed at upper elementary and middle school children and disseminated in non-formal and school settings working in partnership with the National Science Teachers Association Press and the National 4-H Afterschool Council. Undergraduates, graduate students, and postdocs will participate directly in the research project. The euteleosts include some 346 families, 2,935 genera and 17,419 species. Over two thirds of all fishes and nearly a third of all vertebrates are euteleosts, which include most of the economically important fishes such as salmons, basses, cods and tunas. This study will facilitate informed predictions about the poorly known characteristics of most euteleosts and will considerably improve the evolutionary context for understanding model organisms such as zebrafish, pufferfish, cichlids, medaka, and stickleback, which are central to the burgeoning fields of functional genomics, genetics and evolutionary developmental biology.

该项目将涉及来自八个机构的研究人员，致力于解决真骨鱼类内部的进化关系，真骨鱼类代表了脊椎动物多样性的三分之一以上。一个重要组成部分是对公众进行有关这些动物的重要性、进化历史和多样性的教育。系统发育分析将使用来自代表所有真骨鱼类家族的 1,500 个物种的 20 个基因的 DNA 序列数据，以及来自 300 个真骨鱼类谱系的约 450 个形态特征。由此产生的系统发育假说将用于促进对鱼类多样性进化的理解，并重新评估和修改真骨鱼的系统学。真骨鱼生命树的研究将融入科学教育，以真骨鱼系统发育学为框架，探索鱼类形态、遗传、发育和行为多样性的进化。这将被开发为一本教学指南，即一本“Fish ToL 活动手册”，针对小学高年级和初中生，并与国家科学教师协会出版社和国家 4-H 课后委员会合作，在非正规和学校环境中传播。本科生、研究生和博士后将直接参与该研究项目。真骨鱼包括约 346 科、2,935 属和 17,419 种。超过三分之二的鱼类和近三分之一的脊椎动物是真骨鱼，其中包括大多数具有重要经济意义的鱼类，如鲑鱼、鲈鱼、鳕鱼和金枪鱼。这项研究将有助于对大多数真骨鱼鲜为人知的特征进行明智的预测，并将大大改善了解斑马鱼、河豚、慈鲷、青鳉和棘鱼等模式生物的进化背景，这些模式生物是功能基因组学、遗传学和进化发育生物学新兴领域的核心。