MRI: Acquisition of an Illumina NextSeq 550 System to Support Genomic Research and Research Training at University of Nebraska at Omaha

MRI：采购 Illumina NextSeq 550 系统以支持内布拉斯加大学奥马哈分校的基因组研究和研究培训

• 批准号: 1919574
• 负责人: Guoqing Lu
• 金额: $ 27.88万
• 依托单位: University of Nebraska at Omaha
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-10-01 至 2022-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1919574&HistoricalAwards=false
• 关键词: MRI; Acquisition; Illumina; NextSeq; 550

An award is made to the University of Nebraska at Omaha (UNO) to acquire an Illumina next-generation sequencing (NGS) system in order to improve its research infrastructure. UNO is an emerging doctoral/research institution and is committed to supporting the acquisition of this NGS system and the subsequent establishment of a genomics facility. Utilizing an internal machine that is staffed by a trained technician will allow significant cost savings and ultimately increased utilization of the facility across the campus, within the Omaha area and beyond. The facility will provide training on instrument usage to UNO researchers and external users in the form of workshops, learning modules, and annual symposia. The research and career opportunities to students from underrepresented groups will be offered through well-established, community-serving programs within UNO. The requested instrumentation will support basic research through the application of NGS technology to a broad spectrum of collaborative and interdisciplinary projects. Researchers from across the UNO campus, as well as neighboring institutions, will be able to utilize the NGS system to address a wide range of fundamental scientific questions regarding 1) neural and behavioral systems, 2) conservation genetics and systematics, 3) microbiology and molecular genetics, and 4) molecular interaction and gene regulation. These studies will lead to a better understanding of how genomes regulate complex living systems at cellular or organismal levels and will likely result in new discoveries in areas such as biodiversity and cellular function. The acquisition of the Illumina system will significantly advance a broad array of leading-edge research projects involving high-throughput sequencing and greatly strengthen the university?s research training capacities in genomics and bioinformatics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

内布拉斯加大学奥马哈分校（UNO）获得了一项奖励，以获得Illumina下一代测序（NGS）系统，以改善其研究基础设施。UNO是一个新兴的博士/研究机构，并致力于支持该NGS系统的收购和随后建立基因组学设施。利用由训练有素的技术人员配备的内部机器将大大节省成本，并最终提高整个校园、奥马哈地区和其他地区设施的利用率。该设施将以讲习班、学习单元和年度专题讨论会的形式向联合国办事处研究人员和外部用户提供仪器使用方面的培训。来自代表性不足群体的学生的研究和就业机会将通过联合国大学内完善的社区服务项目提供。所要求的仪器将通过将NGS技术应用于广泛的合作和跨学科项目来支持基础研究。来自UNO校园以及邻近机构的研究人员将能够利用NGS系统来解决广泛的基础科学问题，包括1)神经和行为系统，2)保护遗传学和系统学，3)微生物学和分子遗传学，以及4)分子相互作用和基因调控。这些研究将使人们更好地理解基因组如何在细胞或有机体水平上调控复杂的生命系统，并可能在生物多样性和细胞功能等领域产生新的发现。Illumina系统的收购将显著推进一系列涉及高通量测序的前沿研究项目，并大大加强大学的实力。在基因组学和生物信息学方面的研究培训能力。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。