SBIR Phase I: Optical Mode Conversion for Chemical and Biological Sensing and Analysis

SBIR 第一阶段：用于化学和生物传感与分析的光学模式转换

• 批准号: 0741073
• 负责人: Alexander Raspopin
• 金额: $ 10万
• 依托单位: Senspex, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-01-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0741073&HistoricalAwards=false
• 关键词: SBIR; Phase; Optical; Mode; Conversion

This Small Business Innovation Phase I research project proposes a novel diagnostic tool based upon evanescent field and complementary molecular vibrational spectroscopy methods for rapid detection and analysis of hazardous biological and chemical targets in solution and air. The main characteristic of the proposed approach is the use of evanescent field Surface Enhanced Raman Spectroscopy (SERS) and an active integrating probe with maximized evanescent field of propagating excitation signal created by controlled optical mode shifting in the active sensor region. The investigators propose to develop designs and fabrication methods for planar waveguide mechanisms to reversibly and controllably transfer photonic energy between optical modes within a specified path length. The sensor element will be attached to a Raman identification system to obtain Raman and fluorescence signals. The evanescent field at the sensor-environment interface will interact with biological and chemical molecules adsorbed onto or near the surface.Potential commercial applications of the proposed sensor system for environmental contamination include the possibility of contamination level observation in a large variety of remote locations by the use of fiber optic transmission or wireless network of sensor signals to analytical hardware; development of real-time monitoring equipment for hazardous industrial environments; detection of toxic industrial chemicals spills in commercial/industrial chemical storage and transport locations; and development of the real-time scanning system of the tap water contamination levels in residential and commercial buildings.

这一小型企业创新第一阶段研究项目提出了一种新的诊断工具，该工具基于逝去的场和互补的分子振动光谱方法，用于快速检测和分析溶液和空气中的危险生物和化学目标。该方法的主要特点是使用了消失场表面增强拉曼光谱(SERS)和一个有源积分探头，该探头通过受控的光学模式移动在有源传感器区域产生了传播激励信号的最大消逝场。研究人员建议开发平面波导机制的设计和制造方法，以在指定路径长度内的光学模式之间可逆和可控地传输光子能量。传感器元件将连接到拉曼识别系统，以获得拉曼和荧光信号。传感器-环境界面的瞬变场将与吸附在表面或表面附近的生物和化学分子相互作用。拟议的环境污染传感器系统的潜在商业应用包括：通过光纤传输或传感器信号到分析硬件的无线网络，在多种偏远地点观察污染水平；开发危险工业环境的实时监测设备；检测商业/工业化学品储存和运输地点的有毒工业化学品泄漏；以及开发住宅和商业建筑物自来水污染水平的实时扫描系统。