CAREER: Real-time ultrasound biomicroscopy with optoacoustic arrays

ECCS-0746605 Takashi Buma，特拉华大学智力优势：超声生物显微镜可产生组织微观结构的精美图像，但未能飞跃到广泛的临床应用。 一个主要的技术障碍是缺乏在高超声频率下工作的合适的传感器阵列。这个提议的基本假设是什么？光声？技术可以彻底改变超声生物显微镜系统的成像性能。 用于超声检测的光学技术可以产生传统超声技术无法实现的宽带、大孔径和高度密集的传感器阵列。该职业发展计划的研究目标是（1）开发用于高速数据采集的光声传感器阵列;以及（2）开发用于实时成像的基于光声的阵列扫描仪。该研究涉及设备技术、数据采集技术和图像重建算法。更广泛的影响：教育和推广活动将包括中学生、高中生和教师、本科生和研究生以及继续教育专业人员。高中生和本科生可以进行许多方面的拟议研究。本科生和研究生将获得实践经验与医学成像课程开发的实验室组件。 将这门课程转换为远程学习形式将为继续教育专业人员提供机会。基于网络的远程实验室将提供世界范围内的超声波成像和超声波生物显微镜教学实验。鼓励高中生远程访问超声成像设备将使他们对科学和工程感兴趣。 中学生对工程的热情将通过动手项目、成像演示和当地医院的图尔斯参观来培养？医疗影像设备。随着对更广泛的技术的需求大幅增长，成像技术仍存在重大差距。对社会的潜在好处是深远的，因为有效的成像系统可以影响人类生活的各个方面，从个人的健康和安全到国土安全。

ECCS-0746605Takashi Buma, University of DelawareIntellectual merit: Ultrasound biomicroscopy produces exquisite images of tissue microstructure but has failed to make the leap to widespread clinical use. A major technical obstacle has been the lack of suitable sensor arrays operating at high ultrasonic frequencies. The fundamental hypothesis of this proposal is that ?optoacoustic? technology can revolutionize the imaging performance of ultrasound biomicroscopy systems. Optical techniques for ultrasound detection can produce broadband, large aperture, and highly populated sensor arrays unattainable with conventional ultrasound technology. The research goals of this career development plan are to (1) develop optoacoustic sensor arrays for high speed data acquisition; and (2) develop optoacoustic-based array scanners for real-time imaging. The proposed research involves device technology, data acquisition techniques, and image reconstruction algorithms.Broader impacts: The education and outreach activities will include middle school students, high school students and teachers, undergraduate and graduate students, and continuing education professionals. High school and undergraduate students can perform many aspects of the proposed research. Undergraduate and graduate students will gain hands-on experience with a lab component developed for a medical imaging course. Converting this course to distance-learning format will provide access to continuing education professionals. Web-based remote laboratories will provide world-wide access to instructional experiments on ultrasound imaging and ultrasound biomicroscopy. Encouraging high school students to remotely access the ultrasound imaging equipment will interest them in science and engineering. Enthusiasm for engineering among middle school students will be fostered through hands-on projects, imaging demos, and tours of the local hospital?s medical imaging facilities. Significant gaps remain in imaging technology as the need for a broader array of techniques has grown tremendously. The potential benefits to society are far-reaching, as effective imaging systems can impact all aspects of human life from the health and safety of individuals to homeland security.