Mechanisms of nitrogen and phosphorus activation and functionalization

无机，生物无机和有机化学计划的这一奖项支持塔夫茨大学的Elena V. Rybak-Akimova教授的工作，以建立过渡金属辅助氮和磷的裂解，活化和功能化的机制。 该研究的主要重点是动力学研究（低温，停流调查的快速反应）的低坐标，高反应性钼（III）配合物，能够分裂二氮。 拟议的研究将有助于设计新的工艺，将氮，从二氮，直接进入有机或无机分子，而不需要氨的中间。 从这些研究中获得的理解将用于推动磷的类似过程的发现。 有机磷化合物在催化剂、杀虫剂和酶抑制剂中作为配体是重要的。 本科生、研究生和博士后研究人员将与麻省理工学院和迈阿密大学的科学家合作。 Rybak-Akimova博士是一位动力学专家，他与许多美国和国际科学家一起使用NSF资助的停流仪器。

This award by the Inorganic, Bioinorganic, and Organometallic Chemistry Program supports the work of Professor Elena V. Rybak-Akimova at Tufts University to establish the mechanisms of transition metal assisted cleavage, activation, and functionalization of nitrogen and phosphorus. The major emphasis of the research is on kinetic studies (low-temperature, stopped-flow investigations of rapid reactions) of low coordinate, highly reactive molybdenum(III) complexes that are capable of splitting dinitrogen. The proposed research will contribute to the design of new processes that incorporate nitrogen, from dinitrogen, directly into organic or inorganic molecules without requiring the intermediacy of ammonia. The understanding garnered from these studies will be used to drive the discovery of analogous processes for phosphorus. Organic phosphorus compounds are important as ligands in catalysis and also in insecticides and enzyme inhibitors. Undergraduate, graduate, and postdoctoral researchers will collaborate with scientists at both MIT and the University of Miami. Dr. Rybak-Akimova, an expert kineticist, works with many U.S. and international scientists using NSF-funded stopped-flow instrumentation.