A Sensitive Molecular Detection Platform Based on Self-Assembled Conducting Polymer Nanojunctions in a Carbon Nanotube Network

基于碳纳米管网络中自组装导电聚合物纳米结的灵敏分子检测平台

• 批准号: 0750201
• 负责人: Huixin He
• 金额: $ 36.36万
• 依托单位: Rutgers University Newark
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-02-15 至 2012-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0750201&HistoricalAwards=false
• 关键词: Sensitive; Molecular; Detection; Platform; Based

In this research supported by the Analytical and Surface Chemistry Program, Professor Huixin He and her group seek an extensive understanding of the fundamental mechanism of performance enhancement in a conducting polymer/carbon nanotube composite network, and exploit the highly enhanced composite networks for biosensor applications, especially for multiplex chemical warfare agent detections. By exploiting the salient chemistry of nucleic acids, the surface chemistry and electronic structures of commercially available single walled carbon nanotubes (SWNTs) will be engineered to facilitate the production of highly conductive and highly crystallized interfacial conducting polymers in the composite. The high quality interfacial conducting polymer, will act as an array of conducting polymer nanojunctions, and in turn, modulate the electronic contact junctions between the SWNTs in the composite network. The fundamental knowledge learned will lead to the development of a new molecular detection platform, which will synergistically combine the merits of conducting polymer nanojunctions and carbon nanotube networks. The fast conductance-switch property of the conducting polymer nanojunctions will allow rapid, sensitive, and importantly, selective molecular detection. The remarkable electronic and mechanic properties of carbon nanotubes will confer the conducting polymer nanojunctions with chemical and mechanical stability. The self-assembling capability of the carbon nanotube networks will make the nanojunction fabrication scalable and low cost. This project focuses on development of a novel sensitive multiplex chemical warfare agent detection system, which is of national interest. Given the widespread applications of conducting polymers in numerous analytical platforms, the proposed activities will have far reaching scientific and economic impacts on sensor development of trace-level monitoring of pollutants, drugs, and pathogenic bacteria for health care, homeland security, agriculture, and food industries. The educational plan will bring nanoscience tools and concepts to a wide range of students on a campus known as the most diverse in the nation. The inherently interdisciplinary nature of this research will produce students with exceptional training in nanotechnology, surface chemistry, and molecular sensing. Research activities designed for undergraduates, and high school students will promote more gifted minority students into the nanoscience ranks. Extensive outreach to the Newark area, a minority-dominated region, will raise the public awareness of the impact of nanoscience on technology.

在这项由分析和表面化学项目支持的研究中，Huixin He教授和她的团队寻求对导电聚合物/碳纳米管复合网络性能增强的基本机制的广泛理解，并将高度增强的复合网络用于生物传感器应用，特别是用于多重化学战剂检测。通过利用核酸的显著化学性质，将对市售单壁碳纳米管（SWNT）的表面化学和电子结构进行工程化，以促进在复合材料中产生高导电性和高度结晶的界面导电聚合物。高质量的界面导电聚合物将充当导电聚合物纳米结的阵列，并进而调制复合网络中SWNT之间的电子接触结。所学到的基础知识将导致一种新的分子检测平台的开发，该平台将协同地联合收割机结合导电聚合物纳米结和碳纳米管网络的优点。导电聚合物纳米结的快速电导切换特性将允许快速、灵敏且重要的是选择性的分子检测。碳纳米管优异的电学和力学性能将赋予导电聚合物纳米结化学和力学稳定性。碳纳米管网络的自组装能力将使纳米结制造可扩展且成本低。该项目的重点是开发一种新型的敏感的多功能化学战剂检测系统，这是国家利益。鉴于导电聚合物在众多分析平台中的广泛应用，拟议的活动将对卫生保健，国土安全，农业和食品工业的污染物，药物和病原菌的痕量级监测传感器开发产生深远的科学和经济影响。该教育计划将把纳米科学的工具和概念，以广泛的学生在校园被称为最多样化的国家。这项研究固有的跨学科性质将使学生在纳米技术，表面化学和分子传感方面受到特殊的培训。为本科生和高中生设计的研究活动将促进更多有天赋的少数民族学生进入纳米科学行列。广泛推广到纽瓦克地区，一个少数民族占主导地位的地区，将提高公众对纳米科学对技术的影响的认识。