Special Thematic Program on "Mathematical and Quantitative Oncology"

“数学与定量肿瘤学”专题项目

• 批准号: 0752918
• 负责人: Glenn Webb
• 金额: $ 3.6万
• 依托单位: Vanderbilt University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0752918&HistoricalAwards=false
• 关键词: Special; Thematic; Program; Mathematical; Quantitative

Cancer research is at a critical juncture in the interaction of mathematical and biological knowledge for understanding cancer. Mathematical modeling of cancer dynamics has improved to such an extent that we are at a point where mathematical models can be used to probe cancer etiology and progression and guide experimental research in an informed manner. The combination of multi-scale mathematical modeling techniques and immense computing power affords the possibility of integrating basic cancer biology through genetic, sub-cellular, cellular, tissue, and epidemiologic levels. The continuation of recent research progress in this interdisciplinary field requires the training of young researchers to develop these specialized skills. This two-month program of workshops will help to produce an energetic community of young researchers in this field.The plan of this research program is the organization of multidisciplinary meetings focused on major outstanding problems in oncology. The series of meetings will combine the expertise and intellectual resources of three leading institutes: the Fields Institute in Toronto, the Ontario Institute for Cancer Research, and the Vanderbilt Integrative Cancer Biology Center in Nashville. The direct impact of NSF funding will be the training of a significant number of junior United States researchers (junior faculty, postdoctoral fellows and graduate students), who will gain the opportunity to participate in the workshops. This interdisciplinary program in oncology will bring together researchers in the mathematical/physical sciences, oncologists and cancer biologists to address a range of challenging problems and topics in cancer research.

癌症研究正处于数学和生物学知识相互作用的关键时刻，以了解癌症。 癌症动力学的数学建模已经改进到这样的程度，我们在一个点，数学模型可以用来探测癌症病因和进展，并指导实验研究在知情的方式。多尺度数学建模技术和巨大的计算能力的组合提供了通过遗传、亚细胞、细胞、组织和流行病学水平整合基本癌症生物学的可能性。 在这一跨学科领域的最新研究进展的持续需要年轻的研究人员的培训，以发展这些专业技能。这个为期两个月的研讨会计划将有助于在该领域产生一个充满活力的年轻研究人员社区。该研究计划的计划是组织多学科会议，重点讨论肿瘤学中的主要悬而未决的问题。该系列会议将联合收割机的专业知识和智力资源的三个领先的研究所：领域研究所在多伦多，安大略癌症研究所，和范德比尔特综合癌症生物学中心在纳什维尔。 国家科学基金会资助的直接影响将是培训大量美国初级研究人员（初级教员、博士后研究员和研究生），他们将有机会参加讲习班。这个跨学科的肿瘤学计划将汇集数学/物理科学，肿瘤学家和癌症生物学家的研究人员，以解决癌症研究中的一系列具有挑战性的问题和主题。