Fundamental Studies of Molecules Tethered at Immersed Interfaces Using Overlayer-Enhanced ATR-FTR

使用覆盖层增强 ATR-FTR 对束缚在浸入界面的分子进行基础研究

• 批准号: 0809991
• 负责人: Donald Land
• 金额: $ 33.64万
• 依托单位: University of California-Davis
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-15 至 2012-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0809991&HistoricalAwards=false
• 关键词: Fundamental; Studies; Molecules; Tethered; Immersed

The Analytical and Surface Chemistry (ASC) program of the Division of Chemistry will support the research program of Prof. Donald Land of the University of California at Davis. Prof. Land's research program focuses on the development of an overlayer-enhanced attenuated total reflection Fourier transform infrared (OE-ATR-FTIR) spectroscopy technique for the study of solid interfaces that are immersed in aqueous fluids. This technique offers unique complementary capabilities to currently used surface spectroscopic methods like surface enhanced Raman Scattering (SERS) and Sum Frequency Generation (SFG) Spectroscopy. Prof. Land and his students will perform detailed experimental and modeling studies to optimize the performance of this unique spectroscopy to facilitate its applications for the characterization of biomolecules that are adsorbed to the surface of thin films. The study will provide an excellent educational opportunity for graduate students and postdoctoral trainees to carry out a spectroscopic method development project with the potential to greatly impact studies involving interactions between biomolecules on surfaces and at interfaces.

化学部的分析和表面化学（ASC）计划将支持加州大学戴维斯分校的唐纳德·兰德教授的研究计划。Land教授的研究项目侧重于开发覆盖增强衰减全反射傅里叶变换红外（OE-ATR-FTIR）光谱技术，用于研究浸入水性液体中的固体界面。 该技术为目前使用的表面光谱方法如表面增强拉曼散射（Sers）和和频产生（SFG）光谱提供了独特的补充能力。 兰德教授和他的学生将进行详细的实验和建模研究，以优化这种独特的光谱学的性能，以促进其在表征吸附到薄膜表面的生物分子方面的应用。该研究将为研究生和博士后学员提供一个极好的教育机会，以开展光谱方法开发项目，该项目有可能极大地影响涉及表面和界面上生物分子之间相互作用的研究。