Nonlinear Dynamics of Nanopore Current Oscillations
纳米孔电流振荡的非线性动力学
基本信息
- 批准号:0825661
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-09-15 至 2011-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Oscillatory behavior has been observed for almost all electrochemical systems in a certain range of external parameters. Electrochemical oscillators based on membranes are studied as model systems of oscillatory biological processes, and propagation of action potential in neurons. The intellectual merit of the research supported by the Dynamical Systems Program is to prepare and model a new type of membrane electrochemical oscillators based on single tapered-cone shaped nanopores. In strongly soluble salt solutions e.g. potassium chloride, conical nanopores act as molecular current rectifiers. When traces of sparingly soluble species, such as CaHPO4 are present, the system undergoes an intriguing transformation from DC current flow to quasiperiodic current oscillations when a critical membrane voltage is reached. External parameters will be identified that allow for tuning the frequency of current oscillations in the range between fractions of Hz up to several tens of Hz. The ion current oscillations will also be stable for several hours. The experimental data will be subjected to nonlinear dynamics analysis in order to distinguish random noise from deterministic chaos in these nanosystems, and for the latter case characteristics such as attractor dimension and Lyapunov exponents will be extracted from the recordings. The nonlinear dynamics analysis will be performed in parallel to the phenomenological modeling of ion current oscillations using coupled chemical kinetics differential equations. Universal character of this dissipative system far from equilibrium will be investigated as well.Success of the project will lead to preparation and modeling of a new type of electrochemical oscillators, which could be applied as a working element of an ionic circuit, artificial cells, and sensory systems. The research will also result in nonlinear dynamics characterization of nanopore based electrochemical oscillators, and in better understanding of systems that function far from equilibrium in physiological, water based conditions. Education program of this project is focused on organizing hands-on activities for middle and high school students in nanotechnology at UC Irvine. The outreach activities will be done in collaboration with the UCI School Partnership in Research and Information Technology (SPIRIT) program. Interdisciplinary training in nonlinear dynamics tools, electrochemistry, surface studies, and biophysics will be offered to undergraduate and gradate students.
在一定的外部参数范围内,几乎所有电化学系统都观察到了振荡行为。基于膜的电化学振荡器作为振荡生物过程和神经元动作电位传播的模型系统进行研究。动力系统计划支持的研究的智力价值是制备和建模基于单锥形纳米孔的新型膜电化学振荡器。在强溶性盐溶液中,例如氯化钾,圆锥形纳米孔充当分子电流整流器。当存在微量难溶物质(例如 CaHPO4)时,当达到临界膜电压时,系统会经历从直流电流到准周期电流振荡的有趣转变。将确定外部参数,以允许在几分之一赫兹到几十赫兹之间的范围内调整电流振荡的频率。离子电流振荡也将稳定几个小时。实验数据将接受非线性动力学分析,以便区分这些纳米系统中的随机噪声和确定性混沌,对于后者,将从记录中提取吸引子维数和李亚普诺夫指数等特征。非线性动力学分析将与使用耦合化学动力学微分方程的离子电流振荡唯象建模并行进行。还将研究这种远离平衡的耗散系统的普遍特征。该项目的成功将导致新型电化学振荡器的制备和建模,该振荡器可用作离子电路、人造细胞和传感系统的工作元件。该研究还将对基于纳米孔的电化学振荡器进行非线性动力学表征,并更好地理解在生理、水基条件下远离平衡的系统。该项目的教育计划重点是为加州大学欧文分校的中学生和高中生组织纳米技术的实践活动。外展活动将与 UCI 学校研究和信息技术合作伙伴关系 (SPIRIT) 项目合作完成。将为本科生和研究生提供非线性动力学工具、电化学、表面研究和生物物理学的跨学科培训。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Craig Martens其他文献
Pathogenesis of bovine H5N1 clade 2.3.4.4b infection in macaques
猕猴中牛 H5N1 2.3.4.4b 分支感染的发病机制
- DOI:
10.1038/s41586-025-08609-8 - 发表时间:
2025-01-15 - 期刊:
- 影响因子:48.500
- 作者:
Kyle Rosenke;Amanda Griffin;Franziska Kaiser;Ekaterina Altynova;Reshma Mukesh;Trenton Bushmaker;Meaghan Flagg;Thomas Tipih;Kerry Goldin;Arthur Wickenhagen;Brandi N. Williamson;Shane Gallogly;Shanna S. Leventhal;Tessa Lutterman;Atsushi Okumura;Matthew C. Lewis;Kishore Kanakabandi;Craig Martens;Kwe C. Yinda;Deepashri Rao;Brian J. Smith;Carl Shaia;Greg Saturday;Patrick Hanley;Neeltje van Doremalen;Emmie de Wit;Vincent J. Munster;Heinz Feldmann - 通讯作者:
Heinz Feldmann
Jamaican fruit bats’ competence for Ebola but not Marburg virus is driven by intrinsic differences
牙买加果蝠对埃博拉病毒而非马尔堡病毒的易感性是由内在差异驱动的
- DOI:
10.1038/s41467-025-58305-4 - 发表时间:
2025-03-25 - 期刊:
- 影响因子:15.700
- 作者:
Sarah van Tol;Julia R. Port;Robert J. Fischer;Shane Gallogly;Trenton Bushmaker;Amanda Griffin;Jonathan E. Schulz;Aaron Carmody;Lara Myers;Daniel E. Crowley;Caylee A. Falvo;Jade C. Riopelle;Arthur Wickenhagen;Chad Clancy;Jamie Lovaglio;Carl Shaia;Greg Saturday;Jessica Prado-Smith;Yi He;Justin Lack;Craig Martens;Sarah L. Anzick;Lon V. Kendall;Tony Schountz;Raina K. Plowright;Andrea Marzi;Vincent J. Munster - 通讯作者:
Vincent J. Munster
Asymmetric Spectral Characteristic of Ion Currents in Conical Nanopores
- DOI:
10.1016/j.bpj.2008.12.3839 - 发表时间:
2009-02-01 - 期刊:
- 影响因子:
- 作者:
Matthew Powell;Gael Nguyen;Craig Martens;Zuzanna Siwy - 通讯作者:
Zuzanna Siwy
Two new approaches for electronic structure: Partition Density Functional Theory and Potential Functional Theory
电子结构的两种新方法:配分密度泛函理论和势泛函理论
- DOI:
- 发表时间:
2009 - 期刊:
- 影响因子:0
- 作者:
P. Elliott;K. Burke;R. Wu;Craig Martens - 通讯作者:
Craig Martens
emRickettsia rickettsii/em RoaM negatively regulates expression of a limited number of rickettsial genes
立克次氏体罗阿亚种/立克次氏体罗阿亚种 RoaM 负调控有限数量立克次氏体基因的表达
- DOI:
10.1128/msphere.00077-25 - 发表时间:
2025-04-02 - 期刊:
- 影响因子:3.100
- 作者:
Adam M. Nock;Tina R. Clark;Sarah L. Anzick;Elisabeth A. Meyer;Rebecca Miller;Myndi G. Holbrook;Stacy Ricklefs;Craig Martens;Justin Lack;Ted Hackstadt - 通讯作者:
Ted Hackstadt
Craig Martens的其他文献
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{{ truncateString('Craig Martens', 18)}}的其他基金
Methods for Simulating Nonadiabatic Dynamics with Trajectories
用轨迹模拟非绝热动力学的方法
- 批准号:
1764209 - 财政年份:2018
- 资助金额:
-- - 项目类别:
Standard Grant
Theory and Simulation of Many-Body Quantum Coherence
多体量子相干理论与模拟
- 批准号:
0614005 - 财政年份:2006
- 资助金额:
-- - 项目类别:
Continuing Grant
SGER: Nonstationary Time Series Analysis and Qualitative Nonlinear Dynamics of Nonequilibrium Nanoscale Processes
SGER:非平衡纳米级过程的非平稳时间序列分析和定性非线性动力学
- 批准号:
0533042 - 财政年份:2005
- 资助金额:
-- - 项目类别:
Standard Grant
Theory and Simulation of Condensed Phase Femtodynamics
凝聚相飞动力学理论与仿真
- 批准号:
9874091 - 财政年份:1999
- 资助金额:
-- - 项目类别:
Continuing Grant
Presidential Young Investigator: Vibrational Dynamics and Energy Transfer in Many-Body Chemical Systems
总统青年研究员:多体化学系统中的振动动力学和能量转移
- 批准号:
9058482 - 财政年份:1990
- 资助金额:
-- - 项目类别:
Continuing Grant
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