CRIF: MU Purchase of a Single Crystal X-Ray Diffractometer

该奖项由2009年美国复苏和再投资法案(Public Law 111-5)资助。在化学研究仪器和设施多用户计划(CRIF：MU)的资助下，密歇根大学的Carol A.Fierke教授及其同事Adam J.Matzger、John Montgomery、Vincent L.Pecoraro和Melanie S.Sanford将获得一台具有强大铜源的单晶X射线衍射仪，以获得包括合成有机化学、材料科学和无机化学在内的不同领域的高分辨率结构信息。这台仪器将支持以下方面的教育和研究：金属冠醚化合物生产软材料；测定在催化反应中重要的分子的绝对和相对立体化学；氟化蛋白质的生物性质的合成和表征；高氧化态的晚期金属络合物的机理研究；以及在金属-有机框架中。X射线衍射仪允许准确和精确地测量分子的全部三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这里描述的研究将影响许多领域，包括化学、材料化学和生物化学。该仪器将成为教学和研究不可或缺的一部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor Carol A. Fierke from the University of Michigan and colleagues Adam J. Matzger, John Montgomery, Vincent L. Pecoraro and Melanie S. Sanford will acquire a single crystal X-ray diffractometer with a strong copper source to obtain high-resolution structural information in diverse fields including synthetic organic chemistry, materials science and inorganic chemistry. This instrument will support education and research in complexes from metallacrowns producing soft materials; determination of absolute and relative stereochemistry of molecules important in catalytic reactions; in synthesis and characterization of biological properties of fluorinated proteins; in mechanistic studies of late metal complexes with high oxidation states; and in metal-organic frameworks.An X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here will impact a number of areas, including chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research.