A Multi-Disciplinary Approach to Solve the Inverse Problem of Electro- and Magnetocardiography
解决心电图和心磁图反问题的多学科方法
基本信息
- 批准号:191020717
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:德国
- 项目类别:Research Grants
- 财政年份:2011
- 资助国家:德国
- 起止时间:2010-12-31 至 2014-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
In electrocardiography (ECG), the heart is studied by interpreting voltages measured on the body surface. The spatial accuracy of the ECG can be improved by adding more sensors and by modeling the signals with the help of physics and mathematics. In the inverse problem of ECG, the aim is to estimate the sources of the cardiac electric sources or the electric potential on the surface of the heart from the measured signal at the body surface. This problem is illposed: simplifying assumptions, a-priori information, and regularization are needed.The aim of this project is to increase the value of ECG as a tool for cardiac diagnosis by developing methods for solving the inverse problem of electrocardiography.The first research lead will concentrate on an increase in the reconstruction quality using model-based spatio-temporal regularization techniques. The second approach aims to assess the capability of electro- and magnetocardiographic imaging of reconstructing clinically relevant information in the presence of incomplete models and data. In a third lead, the focus will be on new mathematical approaches like making the solver faster and more effective, which can be achieved by a decomposition of the large-scale ill-conditioned problem. Another aspect is the use of different error norms and regularization schemes.
在心电图(ECG)中,通过解释在身体表面测量的电压来研究心脏。通过增加更多的传感器和借助物理和数学对信号进行建模,可以提高ECG的空间精度。在心电图逆问题中,目的是从体表的测量信号中估计心脏表面上的电势或心脏电源的来源。这个问题是不适定的:简化假设、先验信息和正则化是必需的。本项目的目的是通过开发解决心电图逆问题的方法来提高心电图作为心脏诊断工具的价值。第一个研究领导将集中在使用基于模型的时空正则化技术来提高重建质量。第二种方法旨在评估心电图和心磁图成像在存在不完整模型和数据的情况下重建临床相关信息的能力。在第三个方面,重点将放在新的数学方法上,例如使求解器更快,更有效,这可以通过分解大规模病态问题来实现。另一个方面是使用不同的误差范数和正则化方案。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Professor Dr. Olaf Dössel, Ph.D.其他文献
Professor Dr. Olaf Dössel, Ph.D.的其他文献
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{{ truncateString('Professor Dr. Olaf Dössel, Ph.D.', 18)}}的其他基金
Linking Activation Patterns with Substrate Based Electrogram Characteristics to Develop Individualized Ablation Strategies for Atrial Fibrillation
将激活模式与基于基底的电图特征联系起来,制定针对心房颤动的个体化消融策略
- 批准号:
394433254 - 财政年份:2018
- 资助金额:
-- - 项目类别:
Research Grants
Simultaneous optical and electrical charaterization of cardiac tissue with acute ablation lesions
具有急性消融病变的心脏组织的同时光学和电学表征
- 批准号:
286726745 - 财政年份:2016
- 资助金额:
-- - 项目类别:
Research Grants
Ultra Wideband-Based Imaging Technology for Stroke Detection
用于中风检测的超宽带成像技术
- 批准号:
221837833 - 财政年份:2012
- 资助金额:
-- - 项目类别:
Research Grants
Characterization of the electrophysiological substrate in patients with atrial fibrillation - Role of the restitution of atrial conduction velocity and of the voltage for the development of atrial fibrillation
心房颤动患者电生理基质的表征 - 心房传导速度恢复和电压对心房颤动发展的作用
- 批准号:
183027722 - 财政年份:2011
- 资助金额:
-- - 项目类别:
Research Grants
Merkmalsextraktion und Klassifizierung komplex fraktionierter atrialer Elektrogramme, Assistenz-System für die Katheterablation bei Vorhofflimmern
复杂分割心房电图的特征提取和分类、房颤导管消融辅助系统
- 批准号:
193726987 - 财政年份:2011
- 资助金额:
-- - 项目类别:
Research Grants
Simultane fluoreszenzoptische und elektrische Charakterisierung von atrialem Gewebe
心房组织的同步荧光光学和电学表征
- 批准号:
184837257 - 财政年份:2010
- 资助金额:
-- - 项目类别:
Research Grants
MR-Tomographie an Patienten mit Herzschrittmachern
装有起搏器的患者的磁共振断层扫描
- 批准号:
28013014 - 财政年份:2006
- 资助金额:
-- - 项目类别:
Research Grants
EMV in der Klinik - patientengekoppelte Systeme
诊所中的 EMC - 患者关联系统
- 批准号:
5396449 - 财政年份:2003
- 资助金额:
-- - 项目类别:
Research Grants
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