Bayesian Phylogenetic Diagnostics (BPD): Tools and Analyses for the Diagnosis of Convergence in Bayesian Inference of Phylogeny

贝叶斯系统发育诊断 (BPD)：用于系统发育贝叶斯推断收敛性诊断的工具和分析

• 批准号: 0849861
• 负责人: James Wilgenbusch
• 金额: $ 36.05万
• 依托单位: Florida State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0849861&HistoricalAwards=false
• 关键词: Bayesian; Phylogenetic; Diagnostics; BPD; Tools

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Florida State University has received an award to develop software to conduct phylogenetic analysis. Phylogenetic software helps researchers to understand the evolutionary relationship among species. Phylogeny estimation forms the foundation to most modern biological studies and helps frame researchers? and policy makers? understanding of the distribution, diversity, and conservation of life on this planet. The system will integrate existing and new algorithms of convergence and help researchers analyze and visualize phylogenies. The convergence study and software will be developed over modern high performance computing platforms. The team will take a two-tiered approach, i.e., prototype analyses and software on local computing resources and then scale up to large national computing resources, such as, TeraGrid. It is critical to demonstrate this approach now if members of the life sciences community are to effectively utilize the petascale computing resources being brought on-line in the next three years. The Bayesian Phylogenetics Diagnostics package will be available as a downloadable application, as a web application, as a web service and will be integrated with other services such as the TeraGrid, CIPRES and iPlant. This package will integrate in real-time with phylogenetic packages to give users direct insight into potential problems with the analysis. A large number of input and output formats will allow the package to exchange data with additional phylogenetic packages, statistical analysis and visualization software. Additional information about the project can be found at http://ceb.sc.fsu.edu/bpd.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。佛罗里达州立大学获得了一项开发系统发育分析软件的奖励。系统发育软件帮助研究人员了解物种之间的进化关系。系统发育估计构成了大多数现代生物学研究的基础，并有助于构建研究人员的框架。政策制定者呢？了解这个星球上生命的分布、多样性和保护。该系统将整合现有的和新的收敛算法，并帮助研究人员分析和可视化系统发生。融合研究和软件将在现代高性能计算平台上开发。该团队将采取两层方法，即在本地计算资源上进行原型分析和软件，然后扩展到大型国家计算资源，如TeraGrid。如果生命科学界的成员想要有效地利用即将在未来三年内上线的千万亿次计算资源，那么现在就证明这种方法是至关重要的。贝叶斯系统发育诊断包将作为一个可下载的应用程序，作为一个网络应用程序，作为一个网络服务，并将与其他服务如TeraGrid， CIPRES和iPlant集成。该软件包将与系统发育软件包实时集成，让用户直接了解分析的潜在问题。大量的输入和输出格式将允许该软件包与其他系统发育软件包、统计分析和可视化软件交换数据。有关该项目的更多信息可以在http://ceb.sc.fsu.edu/bpd上找到。