Interface Pressure Sensors for Plaster Cast and Other Biomedical Applications

该提案将使用2009年美国复苏和再投资法案（公法111-5）提供的资金进行奖励，并符合2009年3月20日白宫备忘录第2节中规定的要求，该备忘录题为“确保复苏法案资金的负责任支出”。我还确认，作为认知项目官员，该提案不支持《恢复法》A部分第1604节所述的项目。本计画的研究目标为应用于生物医学的亚公分尺寸无电池无线介面压力感测器。 昏迷综合征是一种非常严重的并发症，发生在一个石膏由于肿胀，并可导致缺血，坏死和严重的神经损伤。 通过本项目中研究和开发的传感器系统，可以通过监测石膏内的皮肤表面压力来预防昏迷综合征。所提出的无线传感器还具有显著数量的其他生物医学应用，包括它们在膝关节植入物、髋关节植入物、假体设计中的使用，它们用于测量患有神经病变的糖尿病患者的足迹压力以及用于预防限制在床或轮椅上的患者的褥疮。 MEMS接口压力传感器将开发一种新的电感耦合策略，其中基于频域的算法补偿传感器和远程传感器之间的距离和方向的变化。研究任务包括无线MEMS传感器的设计和制造，频域和自适应估计算法的评估，无线遥测研究和无线传感器内的模拟铸件，包括血压袖带的实验评估。 该项目的教育阶段包括将重点放在高地公园高中学生的医疗传感器系统的课程项目纳入其中。 该项目还将通过专门的夏季REU计划招募少数民族和女性本科生，为他们提供从事尖端研究的机会，并激励他们攻读研究生课程。

This proposal will be awarded using funds made available by the American Recovery and Reinvestment Act of 2009 (Public Law 111-5), and meets the requirements established in Section 2 of the White House Memorandum entitled, Ensuring Responsible Spending of Recovery Act Funds, dated March 20, 2009. I also affirm, as the cognizant Program Officer, that the proposal does not support projects described in Section 1604 of Division A of the Recovery Act. The research objective of this project focuses on sub-centimeter sized battery-less wireless interface pressure sensors for biomedical application. Compartment Syndrome is a very serious complication that occurs in a cast due to swelling and can cause ischemia, necrosis and serious nerve injuries. With the sensor systems investigated and developed in this project, Compartment Syndrome can be prevented by monitoring the skin surface pressure inside the cast. The proposed wireless sensors also have a significant number of other biomedical applications, including their use in knee implants, hip implants, prosthesis design, their use for measurement of footprint pressures in diabetic patients with neuropathy and for prevention of bed sores in patients confined to beds or wheelchairs. MEMS interface pressure sensors will be developed with a novel inductive coupling strategy in which frequency domain based algorithms compensate for varying distance and orientation between the sensor and remote interrogator. The research tasks include design and fabrication of the wireless MEMS sensors, evaluation of frequency domain and adaptive estimation algorithms, wireless telemetry studies and experimental evaluation of the wireless sensors inside a simulated cast that includes a blood pressure cuff. The educational phase of the project include incorporation of class projects focused on medical sensor systems for school students from the Highland Park High School. The project will also recruit minority and women undergraduate students through a specialized summer REU program, providing them an opportunity to work on cutting edge research and motivating them to pursue graduate studies.