Defining the molecular dialogue underlying stomatal infection during fungal pathogenesis

定义真菌发病过程中气孔感染的分子对话

• 批准号: 0920287
• 负责人: Burton Bluhm
• 金额: $ 50万
• 依托单位: University of Arkansas
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-15 至 2013-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0920287&HistoricalAwards=false
• 关键词: Defining; molecular; dialogue; underlying; stomatal

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Fungal diseases of crops are economically and environmentally costly because they reduce yields and require large-scale applications of fungicides. Many pathogenic fungi enter leaves through stomata, which are pores on leaf surfaces involved in gas exchange and water movement through the plant. The mechanisms through which fungal pathogens sense and penetrate stomata are complex and poorly understood. This project focuses on defining the biochemical and genetic basis of stomatal infection in Cercospora zeae-maydis, a widespread and devastating pathogen of corn. To accomplish this goal, fungal genes involved in infection will be identified, and their functions will be determined. Additionally, plant-derived signals that influence stomatal infection will be identified. This information will provide a clearer understanding of stomatal infection by fungi in general, and a detailed model of how C. zeae-maydis infects corn. By clarifying an often-overlooked component of plant disease, this work will assist efforts to develop new sources of durable resistance against agronomically important plant diseases. Integral to the project is the training of post-doctoral, graduate, and undergraduate students, with particular emphasis placed on broadening the participation of groups currently underrepresented in science. Additionally, the investigators are partnering with the Arkansas Cooperative Extension Service to distribute findings from this project through electronic and print media, regional and national presentations, and direct consultations with stakeholders.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。作物真菌病害在经济和环境上都是昂贵的，因为它们会降低产量，并需要大规模应用杀菌剂。 许多病原真菌通过气孔进入叶片，气孔是叶片表面上的孔，参与植物中的气体交换和水分运动。 真菌病原体感知和穿透气孔的机制是复杂的，知之甚少。 该项目的重点是确定玉米尾孢（Cercospora zeae-maydis）气孔感染的生化和遗传基础，玉米尾孢是一种广泛分布的毁灭性玉米病原体。 为了实现这一目标，将确定与感染有关的真菌基因，并确定它们的功能。 此外，将确定影响气孔感染的植物来源的信号。 这些信息将提供一个更清楚的了解气孔感染真菌一般，和一个详细的模型，如何C。玉蜀黍侵染玉米。 通过澄清植物疾病的一个经常被忽视的组成部分，这项工作将有助于努力开发对农业上重要的植物疾病的持久抗性的新来源。 该项目的组成部分是博士后，研究生和本科生的培训，特别强调扩大目前在科学领域代表性不足的群体的参与。 此外，调查人员正在与阿肯色州合作推广服务合作，通过电子和印刷媒体、区域和国家介绍以及与利益攸关方的直接磋商来分发该项目的调查结果。